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血液透析患者出现不典型临床表现的肺外结核。

Extrapulmonary tuberculosis in a hemodialysis patient with unusual clinical presentation.

机构信息

Department of Nephrology, Kayseri State Hospital, Kayseri, Turkey.

出版信息

Int Urol Nephrol. 2010 Mar;42(1):223-6. doi: 10.1007/s11255-009-9540-2. Epub 2009 Apr 29.

Abstract

The incidence of active tuberculosis in patients undergoing maintenance dialysis for a long time is considerably higher than that in general population. A 39-year-old male treated by hemodialysis three times a week for six months was admitted to the hospital with a painless mass palpable under his right areola. X-ray examination of chest showed a hyperintense lesion. Computed tomography revealed a cystic mass in the superior segment of inferior lobe near the thoracic vertebrae. Needle aspiration of the lesion revealed granulomas and acid-resistant bacteria. Anti-tuberculous therapy was therefore initiated. After eight months the patient was admitted back with paraplegia. Magnetic resonance imaging (MRI) revealed that the lesion defined by computed tomography (CT) was extending to the spinal duct and compressing the spinal cord. A tissue biopsy was performed and granulomas were identified. Mycobacterium tuberculosis grew in the culture. This case suggests that in areas with a high incidence of tuberculosis renal patients in a high-risk group should be examined periodically to exclude insidious infection and reduce morbidity and mortality.

摘要

长期接受维持性血液透析的患者发生活动性肺结核的发病率明显高于一般人群。一名 39 岁男性,每周接受血液透析 3 次,已治疗 6 个月,因右侧乳晕下可触及无痛性肿块而入院。胸部 X 线检查显示高信号病变。计算机断层扫描显示胸椎附近下叶下段的囊性肿块。病变的针吸活检显示肉芽肿和耐酸菌。因此开始进行抗结核治疗。8 个月后,患者因截瘫再次入院。磁共振成像(MRI)显示计算机断层扫描(CT)定义的病变延伸至椎管并压迫脊髓。进行了组织活检,发现了肉芽肿。结核分枝杆菌在培养中生长。该病例提示,在结核病高发地区,处于高危人群的肾患者应定期检查,以排除隐匿性感染,降低发病率和死亡率。

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