Muneef M A, Memish Z, Mahmoud S A, Sadoon S A, Bannatyne R, Khan Y
Dept. of Pediatrics, King Fahad National Guard Hospital, Riyadh, Saudi Arabia.
Scand J Gastroenterol. 2001 May;36(5):528-32. doi: 10.1080/003655201750153412.
Abdominal tuberculosis has varied presentation and can be confused with other conditions.
We report our experience with 46 patients. Charts of patients managed during 1984-97 were reviewed.
Fifty-two percent were women and mean age was 46 years. Presenting symptoms were as follows: fever 70%; abdominal pain 70%; weight loss 68%; abdominal swelling 67%; change in bowel habit 39%; anorexia 30%; and sweating 30%. Common physical signs were as follows: fever 73%; ascites 61%; abdominal mass 13%; and doughy abdomen 9%. Thirty percent of patients either gave past history of TB or presented with active TB of other sites. TB skin test was positive in only 27% of patients. CT scans of abdomen were abnormal in 80%, showing ascites, peritoneal lesions or enlarged nodes. Ascitic fluid was diagnostic for TB on smear/culture in 33%. Peritoneal biopsy was performed by laparoscopy or laparotomy in 61%. It was positive for ganulomas in 97% and for smear/culture in 68%. Forty-two patients recovered after receiving anti-TB therapy for 9-12 months. Four patients died. One died within 1 month of initiation of therapy due to extensive TB, and death in the other 3 was due to unrelated causes.
Abdominal TB should be suspected in patients with fever, abdominal pain and ascites. This condition carries good prognosis if promptly diagnosed and treated.
腹部结核有多种表现形式,可能与其他病症相混淆。
我们报告了46例患者的治疗经验。回顾了1984年至1997年期间接受治疗的患者病历。
52%为女性,平均年龄46岁。主要症状如下:发热70%;腹痛70%;体重减轻68%;腹部肿胀67%;排便习惯改变39%;厌食30%;出汗30%。常见体征如下:发热73%;腹水61%;腹部肿块13%;柔韧感腹部9%。30%的患者有结核病既往史或合并其他部位的活动性结核。结核菌素皮肤试验仅27%的患者呈阳性。腹部CT扫描80%异常,表现为腹水、腹膜病变或淋巴结肿大。腹水涂片/培养诊断结核的阳性率为33%。61%的患者通过腹腔镜或剖腹手术进行腹膜活检。肉芽肿阳性率为97%,涂片/培养阳性率为68%。42例患者接受抗结核治疗9至12个月后康复。4例患者死亡。1例在开始治疗后1个月内死于广泛播散性结核,另外3例死于无关原因。
对发热、腹痛和腹水患者应怀疑腹部结核。如果能及时诊断和治疗,该病预后良好。