Miyazaki T, Kuji N, Sugahara M, Katayama E, Sugiyama T, Iida E
Department of Obstetrics and Gynecology, Ogikubo Hospital, Tokyo.
Nihon Sanka Fujinka Gakkai Zasshi. 1991 Nov;43(11):1496-500.
Five ectopic pregnancies occurred in 75 in vitro fertilization and embryo transfer (IVF-ET) pregnancies (6.7%) in Ogikubo Hospital IVF program between 1985 and 1989. The indication for IVF in 70 pregnancies was a tubal factor. Thirty cases were among 70 pregnancies with hydrosalpinx, and 40 cases were with other tubal conditions. All of the five cases had tubal disease. Four of them had hydrosalpingos. The percentage of ectopic pregnancies for the 30 pregnancies with hydrosalpinx was 13.3%, while for 40 pregnancies with other tubal conditions it was 2.5%. However, there was no significant difference between the two groups. No correlation was found in other parameters including superovulatory methods, oocyte recovery procedure, number of embryos transferred, embryo transfer procedure, and endocrine changes after embryo transfer. In this study, we were unable to identify a difference between ectopic pregnancy and intra-uterine gestation in IVF-ET. However, further study is required to clarify whether hydrosalpinx increases the risk of ectopic pregnancy in IVF-ET.
1985年至1989年间，在荻洼医院体外受精与胚胎移植（IVF-ET）项目的75例妊娠中发生了5例异位妊娠（6.7%）。70例妊娠中IVF的指征为输卵管因素。70例输卵管积水妊娠中有30例，40例为其他输卵管情况。5例均有输卵管疾病。其中4例有输卵管积水。30例输卵管积水妊娠的异位妊娠率为13.3%，而40例其他输卵管情况妊娠的异位妊娠率为2.5%。然而，两组之间无显著差异。在其他参数中未发现相关性，包括超排卵方法、卵母细胞回收程序、移植胚胎数量、胚胎移植程序以及胚胎移植后的内分泌变化。在本研究中，我们未能确定IVF-ET中异位妊娠与宫内妊娠之间的差异。然而，需要进一步研究以阐明输卵管积水是否会增加IVF-ET中异位妊娠的风险。
