Tinga D J, Simons A H
Academisch Ziekenhuis, afd. Obstetrie en Gynaecologie, Groningen.
Ned Tijdschr Geneeskd. 1994 Jan 22;138(4):193-6.
Determination of the difference in percentages of ectopic pregnancies in patients with and without tubal pathology after in-vitro fertilisation and consequences for prevention.
Thirteen IVF clinics in the Netherlands.
The clinics submitted data on clinical and ectopic pregnancies and the indication for IVF from the years 1990 and 1991.
The indication in 1075 cases of IVF-clinical pregnancies was a tubal factor and in 990 cases of IVF-clinical pregnancies another (non-tubal) factor. Percentages of ectopic pregnancies in these groups were 4.5 and 1.1 respectively (significant difference: relative risk: 4.02; 95% confidence interval: 2.10-7.69). One case of heterotopic pregnancy had occurred. No particular type of tubal pathology with high risk for ectopic pregnancy could be identified.
Preventive salpingectomy before the IVF procedure in patients with a tubal factor is not justified.
确定体外受精后有输卵管病变和无输卵管病变患者异位妊娠百分比的差异及其预防意义。
荷兰的13家体外受精诊所。
这些诊所提交了1990年和1991年关于临床妊娠和异位妊娠的数据以及体外受精的指征。
1075例体外受精临床妊娠的指征为输卵管因素，990例体外受精临床妊娠的指征为其他（非输卵管）因素。这些组中异位妊娠的百分比分别为4.5%和1.1%（显著差异：相对风险：4.02；95%置信区间：2.10 - 7.69）。发生了1例异位妊娠。未发现有异位妊娠高风险的特定类型输卵管病变。
对于有输卵管因素的患者，在体外受精手术前进行预防性输卵管切除术是不合理的。
