McCaughey Ryan G, Sun Hui, Rothholtz Vanessa S, Juhasz Tibor, Wong Brian J F
University of California, Irvine, Beckman Laser Institute and Medical Clinic, 1002 Health Sciences Road, Irvine, Calfornia 92612, USA.
J Biomed Opt. 2009 Mar-Apr;14(2):024040. doi: 10.1117/1.3120490.
A femtosecond laser, normally used for LASIK eye surgery, is used to perforate cadaveric human stapes. The thermal side effects of bone ablation are measured with a thermocouple in an inner ear model and are found to be within acceptable limits for inner ear surgery. Stress and acoustic events, recorded with piezoelectric film and a microphone, respectively, are found to be negligible. Optical microscopy, scanning electron microscopy, and optical coherence tomography are used to confirm the precision of the ablation craters and lack of damage to the surrounding tissue. Ablation is compared to that from an Er:YAG laser, the current laser of choice for stapedotomy, and is found to be superior. Ultra-short-pulsed lasers offer a precise and efficient ablation of the stapes, with minimal thermal and negligible mechanical and acoustic damage. They are, therefore, ideal for stapedotomy operations.
一种通常用于准分子激光原位角膜磨镶术(LASIK)眼部手术的飞秒激光,被用于在尸体人类镫骨上打孔。在内耳模型中用热电偶测量骨消融的热副作用,发现其在内耳手术的可接受范围内。分别用压电薄膜和麦克风记录的应力和声事件被发现可忽略不计。光学显微镜、扫描电子显微镜和光学相干断层扫描被用于确认消融坑的精度以及对周围组织无损伤。将该消融与铒钇铝石榴石(Er:YAG)激光(目前镫骨切除术的首选激光)的消融进行比较,发现前者更具优势。超短脉冲激光能对镫骨进行精确且高效的消融,热损伤最小,机械和声损伤可忽略不计。因此,它们是镫骨切除术的理想选择。