Centelles-Serrano María José, Pérez-Moreno Mar Olga, Llovet-Lombarte María Isabel, Cortell-Ortolá María, Jardí-Baiges Anna Maria, Buj-González José Ignacio
Hospital de Tortosa Verge de la Cinta, Tarragona, España.
Enferm Infecc Microbiol Clin. 2009 Aug-Sep;27(7):394-8. doi: 10.1016/j.eimc.2008.10.004. Epub 2009 May 5.
To evaluate the effectiveness of systematic investigation for Group B Streptococcus (GBS) in urine samples to detect colonization in pregnant women.
This study included 1036 pregnant women whose urine samples were cultured in our laboratory during 2006. Any colony consistent with GBS was identified in urine or in rectovaginal samples submitted for screening of GBS colonization.
GBS was recovered in urine samples from 111 of the 1036 women (10.7%), and in 77 of them bacterial count was <10(4) colony forming units/mL. Screening for GBS in rectovaginal samples was performed in 841 of the 925 pregnant women who did not have GBS bacteriuria (10.1% positive results) and in 61 of the 111 with GBS bacteriuria (60.7% positive results; no significant differences were found when results were stratified by colony count). Estimated rectovaginal colonization was 15.4%, and colonization exclusively detected in urine was 4.2%. Only 30% of pregnant women with GBS bacteriuria, but negative antenatal screening cultures who were admitted to our hospital for delivery received intrapartum antibiotic prophylaxis.
Systematic investigation of the presence of GBS in urine samples from pregnant women improves the detection of carriers who are candidates for receiving intrapartum prophylaxis to prevent perinatal GBS infection, when compared with rectovaginal screening culture in the last trimester of gestation alone.
评估对孕妇尿液样本进行B族链球菌（GBS）系统检测以发现定植情况的有效性。
本研究纳入了2006年在我们实验室进行尿液样本培养的1036名孕妇。在尿液或提交用于GBS定植筛查的直肠阴道样本中，鉴定出任何与GBS相符的菌落。
1036名女性中有111名（10.7%）的尿液样本中检测到GBS，其中77人的细菌计数<10⁴菌落形成单位/毫升。在925名无GBS菌尿的孕妇中，有841名进行了直肠阴道样本GBS筛查（阳性结果为10.1%），在111名有GBS菌尿的孕妇中，有61名进行了筛查（阳性结果为60.7%；按菌落计数分层时未发现显著差异）。估计直肠阴道定植率为15.4%，仅在尿液中检测到的定植率为4.2%。在我院入院分娩的GBS菌尿但产前筛查培养阴性的孕妇中，只有30%接受了产时抗生素预防。
与仅在妊娠晚期进行直肠阴道筛查培养相比，对孕妇尿液样本中GBS的存在进行系统检测可提高对有产时预防以预防围产期GBS感染的携带者的检测率。
