Bye E, Føreland S, Lundgren L, Kruse K, Rønning R
Department of Chemical and Biological Working Environment, National Institute of Occupational Health, PO Box 8149 Dep., N-0033 Oslo, Norway.
Ann Occup Hyg. 2009 Jun;53(4):403-8. doi: 10.1093/annhyg/mep022. Epub 2009 Apr 30.
The purpose of the present investigation was to establish a method for the determination of airborne respirable non-fibrous silicon carbide (SiC). The main application is within the industrial production of SiC.
Due to the complex airborne aerosol mixture of crystalline compounds in the SiC industry, X-ray powder diffractometry was selected as the most appropriate method. Without any international standard material for the respirable fraction of non-fibrous SiC, pure and suitable products from three SiC plants in Norway were selected. These products have a median particle diameter in the range 4.4-5.1 mum. The method is based on thin sample technique, with the dust deposited on a polycarbonate filter. Absorption correction is done by standard procedures with the use of a silver filter, situated below the polycarbonate filter.
The diffraction line used for quantitative determination was selected carefully. This was done to avoid interferences from quartz, cristobalite, and graphite, which all are airborne components present in the atmosphere during the industrial process. The instrumental limit of detection for the method is 12 microg.
This method has been used to determine airborne non-fibrous SiC in a comprehensive ongoing project in the Norwegian SiC industry for further epidemiological studies. The method is fully applicable for compliance work.
本研究的目的是建立一种测定空气中可吸入的非纤维状碳化硅（SiC）的方法。其主要应用于SiC的工业生产中。
由于SiC行业中空气中晶体化合物气溶胶混合物的复杂性，X射线粉末衍射法被选为最合适的方法。由于没有非纤维状SiC可吸入部分的任何国际标准物质，因此选择了挪威三家SiC工厂的纯净且合适的产品。这些产品的中位粒径在4.4 - 5.1微米范围内。该方法基于薄样品技术，灰尘沉积在聚碳酸酯滤膜上。通过使用位于聚碳酸酯滤膜下方的银滤膜，采用标准程序进行吸收校正。
仔细选择了用于定量测定的衍射线。这样做是为了避免来自石英、方石英和石墨的干扰，这些都是工业过程中大气中存在的空气传播成分。该方法的仪器检测限为12微克。
该方法已用于挪威SiC行业一个正在进行的综合项目中，以测定空气中的非纤维状SiC，用于进一步的流行病学研究。该方法完全适用于合规工作。
