Schweitzer Mary H, Zheng Wenxia, Organ Chris L, Avci Recep, Suo Zhiyong, Freimark Lisa M, Lebleu Valerie S, Duncan Michael B, Vander Heiden Matthew G, Neveu John M, Lane William S, Cottrell John S, Horner John R, Cantley Lewis C, Kalluri Raghu, Asara John M
North Carolina State University, Raleigh, NC 27695, USA.
Science. 2009 May 1;324(5927):626-31. doi: 10.1126/science.1165069.
Molecular preservation in non-avian dinosaurs is controversial. We present multiple lines of evidence that endogenous proteinaceous material is preserved in bone fragments and soft tissues from an 80-million-year-old Campanian hadrosaur, Brachylophosaurus canadensis [Museum of the Rockies (MOR) 2598]. Microstructural and immunological data are consistent with preservation of multiple bone matrix and vessel proteins, and phylogenetic analyses of Brachylophosaurus collagen sequenced by mass spectrometry robustly support the bird-dinosaur clade, consistent with an endogenous source for these collagen peptides. These data complement earlier results from Tyrannosaurus rex (MOR 1125) and confirm that molecular preservation in Cretaceous dinosaurs is not a unique event.
非鸟类恐龙的分子保存存在争议。我们提供了多条证据表明，在一具距今8000万年的坎帕阶鸭嘴龙（短冠龙）的骨骼碎片和软组织中保存有内源性蛋白质物质[落基山博物馆（MOR）2598]。微观结构和免疫学数据与多种骨基质和血管蛋白的保存情况一致，通过质谱法对短冠龙胶原蛋白进行的系统发育分析有力地支持了鸟类 - 恐龙进化枝，这与这些胶原蛋白肽的内源性来源一致。这些数据补充了霸王龙（MOR 1125）早期的研究结果，并证实白垩纪恐龙中的分子保存并非个别现象。
