家族性慢性淋巴细胞白血病的分子基础。
The molecular basis of familial chronic lymphocytic leukemia.
作者信息
Crowther-Swanepoel Dalemari, Houlston Richard S
出版信息
Haematologica. 2009 May;94(5):606-9. doi: 10.3324/haematol.2009.006296.
Abstract
Our understanding of the genetic basis of chronic lymphocytic leukemia is only just starting to be recognized. This perspective article by Drs. Crowther-Swanepoel and Houlston provides an up-to-date review the molecular epidemiology of chronic lymphocytic leukemia, with emphasis on the integration of biology and genomics.
摘要
我们对慢性淋巴细胞白血病遗传基础的理解才刚刚开始得到认识。克劳瑟 - 斯瓦内普尔博士和豪尔斯顿博士撰写的这篇观点文章对慢性淋巴细胞白血病的分子流行病学进行了最新综述，重点在于生物学与基因组学的整合。
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本文引用的文献
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Molecular evidence for EBV and CMV persistence in a subset of patients with chronic lymphocytic leukemia expressing stereotyped IGHV4-34 B-cell receptors.EB病毒和巨细胞病毒在一部分表达定型IGHV4-34 B细胞受体的慢性淋巴细胞白血病患者中持续存在的分子证据。
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