Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Surg Today. 2009;39(5):452-5. doi: 10.1007/s00595-008-3857-9. Epub 2009 Apr 30.
Most liver hemangiomas are small, asymptomatic, and require no treatment. Symptoms such as right upper quadrant abdominal pain and fullness are associated only with liver hemangiomas larger than 4 cm in diameter. Serious complications such as jaundice, Kasabach-Merritt syndrome, and rupture are rare. Surgical resection is the only effective treatment, but it is advocated only for patients with incapacitating symptoms or complications. We report a case of successful superextended hepatectomy with resection of segments III-VIII for multiple, bilobar hemangiomas. A 45-year-old woman, who had undergone transcatheter arterial embolization (TAE) for inoperable multiple giant liver hemangiomas 4 years earlier, was referred to our hospital for investigation of abdominal distension and consumption coagulopathy. Because of her severe and progressive symptoms despite treatment, the other hospital had considered her as a candidate for liver transplantation, which she had refused. After careful preoperative assessment of the future liver remnant volume and function, we considered that resection was possible. Based on our review of large surgical series in the literature from 1970, this is the first report of a superextended hepatectomy for a benign liver tumor.
大多数肝血管瘤体积较小,无明显症状,无需治疗。右上腹疼痛和饱胀等症状仅与直径大于 4 厘米的肝血管瘤有关。严重并发症如黄疸、卡-梅二氏综合征和破裂较为罕见。手术切除是唯一有效的治疗方法,但仅适用于有症状或并发症的患者。我们报告了一例成功的超扩大肝切除术,用于治疗多发性、双侧肝血管瘤。一名 45 岁女性,4 年前因不可切除的多发性巨大肝血管瘤行经导管动脉栓塞术(TAE),因腹胀和消耗性凝血病就诊。尽管进行了治疗,但由于症状严重且进行性加重,另一家医院曾考虑将她作为肝移植的候选者,但她拒绝了。仔细评估未来肝脏残余体积和功能后,我们认为可以进行手术切除。根据我们对 1970 年以来文献中大手术系列的回顾,这是首例报道的良性肝肿瘤超扩大肝切除术。