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经导管动脉栓塞有效减容后行三分切除术切除巨大肝血管瘤:一例报告

Giant liver hemangioma resected by trisectorectomy after efficient volume reduction by transcatheter arterial embolization: a case report.

作者信息

Akamatsu Nobuhisa, Sugawara Yasuhiko, Komagome Masahiko, Ishida Takashi, Shin Nobuhiro, Cho Narihiro, Ozawa Fumiaki, Hashimoto Daijo

机构信息

Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

出版信息

J Med Case Rep. 2010 Aug 23;4:283. doi: 10.1186/1752-1947-4-283.

Abstract

INTRODUCTION

Liver hemangiomas are the most common benign liver tumors, usually small in size and requiring no treatment. Giant hemangiomas complicated with consumptive coagulopathy (Kasabach-Merritt syndrome) or causing severe incapacitating symptoms, however, are generally considered an absolute indication for surgical resection. Here, we present the case of a giant hemangioma, which was, to the best of our knowledge, one of the largest ever reported.

CASE PRESENTATION

A 38-year-old Asian man was referred to our hospital with complaints of severe abdominal distension and pancytopenia. Examinations at the first visit revealed a right liver hemangioma occupying the abdominal cavity, protruding into the right diaphragm up to the right thoracic cavity and extending down to the pelvic cavity, with a maximum diameter of 43 cm, complicated with "asymptomatic" Kasabach-Merritt syndrome. Based on the tumor size and the anatomic relationship between the tumor and hepatic vena cava, primary resection seemed difficult and dangerous, leading us to first perform transcatheter arterial embolization to reduce the tumor volume and to ensure the safety of future resection. The tumor volume was significantly decreased by two successive transcatheter arterial embolizations, and a conventional right trisectorectomy was then performed without difficulty to resect the tumor.

CONCLUSIONS

To date, there have been several reports of aggressive surgical treatments, including extra-corporeal hepatic resection and liver transplantation, for huge hemangiomas like the present case, but because of its benign nature, every effort should be made to avoid life-threatening surgical stress for patients. Our experience demonstrates that a pre-operative arterial embolization may effectively enable the resection of large hemangiomas.

摘要

引言

肝血管瘤是最常见的肝脏良性肿瘤,通常体积较小,无需治疗。然而,巨大血管瘤合并消耗性凝血病(卡萨巴赫-梅里特综合征)或引起严重失能症状时,一般被视为手术切除的绝对指征。在此,我们报告一例巨大肝血管瘤病例,据我们所知,该病例是有报道以来最大的病例之一。

病例介绍

一名38岁的亚洲男性因严重腹胀和全血细胞减少症被转诊至我院。首次就诊时的检查发现,右肝血管瘤占据腹腔,向上突入右膈肌直至右胸腔,并向下延伸至盆腔,最大直径达43 cm,合并“无症状”卡萨巴赫-梅里特综合征。基于肿瘤大小以及肿瘤与肝静脉的解剖关系,初次切除似乎困难且危险,这促使我们首先进行经导管动脉栓塞术以缩小肿瘤体积,并确保未来切除手术的安全性。通过连续两次经导管动脉栓塞术,肿瘤体积显著减小,随后顺利进行了传统的右半肝切除术以切除肿瘤。

结论

迄今为止,已有多篇关于针对如本病例这样的巨大血管瘤进行积极手术治疗的报道,包括体外肝切除和肝移植,但由于其良性性质,应尽一切努力避免给患者带来危及生命的手术应激。我们的经验表明,术前动脉栓塞术可能有效地实现对大型血管瘤的切除。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e1d/2936318/1da191c337d6/1752-1947-4-283-1.jpg

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