Hong Jae Hee, Omur-Ozbek Pinar, Stanek Brian T, Dietrich Andrea M, Duncan Susan E, Lee Yong Woo, Lesser Glenn
Department of Food Science and Technology, Virginia Tech, Blacksburg, Virginia 24061, USA.
J Support Oncol. 2009 Mar-Apr;7(2):58-65.
Taste and odor abnormalities are major daily concerns for patients with cancer. This review summarizes the common taste and odor disorders of cancer patients and provides insight into their possible causes. Cancer and its therapy, including chemotherapy and radiotherapy, may directly alter and damage taste and odor perception.These alterations affect the daily quality of life of these patients and may lead to patient malnutrition and, in severe cases, significant morbidity. Cancer patients experience decreases in sensitivity to taste and odor, as well as unpleasant metallic and bitter sensations. Complaints relating to taste and odor are not usually addressed, as few, if any, effective interventions are available for these problems. Understanding the types and causes of taste and odor dysfunctions will enable researchers and physicians to develop treatments for these conditions and thereby improve patient quality of life.
味觉和嗅觉异常是癌症患者日常主要关注的问题。本综述总结了癌症患者常见的味觉和嗅觉障碍，并深入探讨了其可能的病因。癌症及其治疗，包括化疗和放疗，可能直接改变和损害味觉和嗅觉感知。这些改变影响了这些患者的日常生活质量，可能导致患者营养不良，严重时还会引发严重疾病。癌症患者对味觉和嗅觉的敏感度下降，同时还会出现令人不适的金属味和苦味。由于针对这些问题几乎没有有效的干预措施，因此与味觉和嗅觉相关的投诉通常得不到解决。了解味觉和嗅觉功能障碍的类型和原因将使研究人员和医生能够开发针对这些病症的治疗方法，从而提高患者的生活质量。
