Jacq Fanny, Foulldrin Gael, Savouré Arnaud, Anselme Frédéric, Baguelin-Pinaud Audrey, Cribier Alain, Thibaut Florence
Department of Psychiatry, INSERM U 614, University Hospital Ch. Nicolle, University of Medicine, Rouen, France.
Gen Hosp Psychiatry. 2009 May-Jun;31(3):266-73. doi: 10.1016/j.genhosppsych.2009.01.003. Epub 2009 Mar 19.
Using standardized scales, we assessed the point prevalence, the severity of anxiety and depressive disorders, and the quality of life (QOL) in implantable cardioverter defibrillator (ICD) recipients who received a device shock.
Forty research subjects with device shocks (Group 1) and 25 without shocks (Group 2) were interviewed after ICD implantation using the Mini International Neuropsychiatric Interview (MINI), the Hospital Anxiety and Depression Scale (HADS) and the Medical Outcomes Study 36-Item Short Form Health Survey (SF-36).
The point prevalence of anxiety disorders was higher in Group 1 (37.5%) than in Group 2 (8%) (P=.009). Depressive symptoms scores were higher in Group 1 (4.75) than in Group 2 (2.24) (P=.04)), but the prevalence of depressive disorders or the anxiety scores were not significantly different. A positive correlation was found between the number of shocks and the depressive symptoms scores (P=.05, r=0.24); there was a negative correlation between the mental health subscore of the SF-36 and the number of shocks (r=-0.36, P=.003). The point prevalence of depressive disorders was higher in the group with congenital cardiac diseases (50%) than in the valvular (8%) and ischemic groups (23%) (P=.04), and the mental health composite summary score of the SF-36 was lower in this group (46.34) than in those with valvular and ischemic disease (56.09 and 52.61, respectively) (P=.03).
Exposure to shocks may lead to an increased risk of anxiety and depressive symptoms. Research subjects receiving a high number of shocks and research subjects with congenital cardiovascular diseases were at higher risk of depressive symptoms or at higher risk of poorer psychological aspects of QOL.
我们使用标准化量表评估了接受植入式心脏复律除颤器(ICD)电击治疗的患者的时点患病率、焦虑和抑郁障碍的严重程度以及生活质量(QOL)。
在ICD植入后,使用迷你国际神经精神访谈(MINI)、医院焦虑抑郁量表(HADS)和医学结局研究36项简短健康调查(SF - 36)对40名有电击治疗的研究对象(第1组)和25名无电击治疗的研究对象(第2组)进行访谈。
第1组焦虑障碍的时点患病率(37.5%)高于第2组(8%)(P = 0.009)。第1组的抑郁症状评分(4.75)高于第2组(2.24)(P = 0.04),但抑郁障碍的患病率或焦虑评分无显著差异。电击次数与抑郁症状评分之间存在正相关(P = 0.05,r = 0.24);SF - 36心理健康子量表评分与电击次数之间存在负相关(r = - 0.36,P = 0.003)。先天性心脏病组抑郁障碍的时点患病率(50%)高于瓣膜病组(8%)和缺血性心脏病组(23%)(P = 0.04),且该组SF - 36心理健康综合汇总评分(46.34)低于瓣膜病组和缺血性心脏病组(分别为56.09和52.61)(P = 0.03)。
接受电击治疗可能会增加焦虑和抑郁症状的风险。接受多次电击治疗的研究对象以及患有先天性心血管疾病的研究对象出现抑郁症状的风险更高,或者生活质量的心理方面较差的风险更高。