• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

泡状脊索瘤继发脑脊液鼻漏。

Cerebrospinal fluid rhinorrhea secondary to ecchordosis physaliphora.

作者信息

Alli Adebayo, Clark Matthew, Mansell Nicholas J

机构信息

Department of Anatomy, Academic Centre, Henriette Raphael Building, Guy's Campus, King's College, London, United Kingdom.

出版信息

Skull Base. 2008 Nov;18(6):395-9. doi: 10.1055/s-0028-1087221.

DOI:10.1055/s-0028-1087221
PMID:19412409
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2637074/
Abstract

Ecchordosis physaliphora is a rare hamartomatous lesion of notochord origin that is usually asymptomatic. In this case report, such a lesion arose at the clivus, with extension through to the sphenoid sinus. As a result, it presented with cerebrospinal fluid rhinorhea, making the case particularly unusual. We describe the treatment for this rare situation and discuss its differentiation from chordoma, its malignant counterpart.

摘要

泡状脊索瘤是一种罕见的起源于脊索的错构瘤性病变,通常无症状。在本病例报告中,这样的病变发生于斜坡,延伸至蝶窦。结果,它表现为脑脊液鼻漏,使该病例尤为特殊。我们描述了针对这种罕见情况的治疗方法,并讨论了它与脊索瘤(其恶性对应物)的鉴别诊断。

相似文献

1
Cerebrospinal fluid rhinorrhea secondary to ecchordosis physaliphora.泡状脊索瘤继发脑脊液鼻漏。
Skull Base. 2008 Nov;18(6):395-9. doi: 10.1055/s-0028-1087221.
2
Cerebrospinal fluid fistula secondary to ecchordosis physaliphora.脊索瘤继发脑脊液瘘
Neurosurgery. 1990 Mar;26(3):515-8; discussion 518-9. doi: 10.1097/00006123-199003000-00022.
3
Ecchordosis physaliphora: Case report and brief review of the literature.泡状脊索瘤:病例报告及文献简要综述
Radiol Case Rep. 2021 Oct 17;16(12):3937-3939. doi: 10.1016/j.radcr.2021.09.049. eCollection 2021 Dec.
4
Do All Notochordal Lesions Require Proton Beam Radiotherapy? A Proposed Reclassification of Ecchordosis Physaliphora as Benign Notochord Cell Tumor.所有脊索瘤样病变都需要质子束放疗吗?拟将黏液样脊索瘤重新分类为良性脊索细胞瘤。
J Neurol Surg B Skull Base. 2021 Mar 12;83(Suppl 2):e96-e104. doi: 10.1055/s-0040-1722717. eCollection 2022 Jun.
5
Ecchordosis physaliphora: a cautionary tale.泡状脊索瘤:一则警示故事。
J Laryngol Otol. 2020 Jan;134(1):46-51. doi: 10.1017/S0022215119002512. Epub 2019 Dec 20.
6
Spontaneous rhinorrhea: a possible concealing initial symptom of ecchordosis physaliphora. Illustrative case.自发性鼻溢液:泡状脊索瘤一种可能隐匿的初始症状。病例说明。
J Neurosurg Case Lessons. 2023 Mar 27;5(13). doi: 10.3171/CASE236.
7
Ecchordosis physaliphora - a case report and a review of notochord-derived lesions.脊索瘤病——病例报告及脊索源性病变综述。
Neurol Neurochir Pol. 2011 Mar-Apr;45(2):169-73. doi: 10.1016/s0028-3843(14)60029-3.
8
Endoscopic resection of a giant intradural retroclival ecchordosis physaliphora: surgical technique and literature review.内镜切除巨大椎管内硬膜后室管膜瘤:手术技术及文献复习。
World Neurosurg. 2014 Nov;82(5):912.e21-6. doi: 10.1016/j.wneu.2014.06.019. Epub 2014 Jun 14.
9
Spontaneous cerebrospinal fluid rhinorrhoea with meningitis secondary to ecchordosis physaliphora.脊索球蚴病继发自发性脑脊液鼻漏伴脑膜炎
Br J Neurosurg. 2019 Feb;33(1):99-100. doi: 10.1080/02688697.2017.1297766. Epub 2017 Mar 2.
10
Successful endoscopic endonasal management of a transclival cerebrospinal fluid fistula secondary to ecchordosis physaliphora--an ectopic remnant of primitive notochord tissue in the clivus.经鼻内镜成功治疗继发于垂体脊索瘤(斜坡处原始脊索组织的异位残余物)的经斜坡脑脊液漏。
Clin Neurol Neurosurg. 2014 Feb;117:116-119. doi: 10.1016/j.clineuro.2013.11.026. Epub 2013 Dec 7.

引用本文的文献

1
Notochord-derived lesion presenting with cerebrospinal fluid rhinorrhea: illustrative case.以脑脊液鼻漏为表现的脊索源性病变:病例说明
J Neurosurg Case Lessons. 2025 Jun 2;9(22). doi: 10.3171/CASE25157.
2
An Ecchordosis Physaliphora, a Rare Entity, Involving the Central Nervous System: A Systematic Review of the Literature.一种累及中枢神经系统的罕见实体——泡状脊索瘤:文献系统综述
Neurol Int. 2023 Sep 26;15(4):1200-1211. doi: 10.3390/neurolint15040075.
3
Spontaneous rhinorrhea: a possible concealing initial symptom of ecchordosis physaliphora. Illustrative case.自发性鼻溢液:泡状脊索瘤一种可能隐匿的初始症状。病例说明。
J Neurosurg Case Lessons. 2023 Mar 27;5(13). doi: 10.3171/CASE236.
4
Chronic cerebrospinal fluid rhinorrhea as an initial presentation of chordoma: illustrative case.慢性脑脊液鼻漏作为脊索瘤的首发表现:病例报告
J Neurosurg Case Lessons. 2023 Apr 3;5(14). doi: 10.3171/CASE2347.
5
Chordoma of the Clivus with Metastasis to Femur.斜坡脊索瘤伴股骨转移
Asian J Neurosurg. 2022 Oct 12;17(3):536-540. doi: 10.1055/s-0042-1756629. eCollection 2022 Sep.
6
Do All Notochordal Lesions Require Proton Beam Radiotherapy? A Proposed Reclassification of Ecchordosis Physaliphora as Benign Notochord Cell Tumor.所有脊索瘤样病变都需要质子束放疗吗?拟将黏液样脊索瘤重新分类为良性脊索细胞瘤。
J Neurol Surg B Skull Base. 2021 Mar 12;83(Suppl 2):e96-e104. doi: 10.1055/s-0040-1722717. eCollection 2022 Jun.
7
Proposed Diagnostic Criteria, Classification Schema, and Review of Literature of Notochord-Derived Ecchordosis Physaliphora.脊索源性泡状脊索瘤的拟诊标准、分类方案及文献综述
Cureus. 2016 Mar 30;8(3):e547. doi: 10.7759/cureus.547.
8
Diagnostic imaging dilemma of a clival lesion and its clinical management implications.斜坡病变的诊断性影像学难题及其临床管理意义。
J Neurol Surg B Skull Base. 2014 Jun;75(3):177-82. doi: 10.1055/s-0033-1363171. Epub 2014 Mar 3.
9
Transclival pseudomeningocele secondary to ecchordosis physaliphora: case report and literature review.继发于黏液样脊索瘤的经斜坡假性脊膜膨出:病例报告及文献复习
J Neurol Surg Rep. 2013 Dec;74(2):92-5. doi: 10.1055/s-0033-1348956. Epub 2013 Sep 9.
10
From notochord formation to hereditary chordoma: the many roles of Brachyury.从脊索形成到遗传性脊索瘤:Brachyury 的多种作用。
Biomed Res Int. 2013;2013:826435. doi: 10.1155/2013/826435. Epub 2013 Mar 31.

本文引用的文献

1
Juvenile intradural chordoma: case report.青少年硬膜内脊索瘤:病例报告
Neurosurgery. 2008 Feb;62(2):E525-6; discussion E527. doi: 10.1227/01.neu.0000316022.74162.00.
2
A case of giant ecchordosis physaliphora: a case report and literature review.一例巨大泡状脊索瘤病例报告及文献复习
Otol Neurotol. 2007 Oct;28(7):931-3. doi: 10.1097/MAO.0b013e318068b2c8.
3
Intracranial neurenteric cysts: imaging and pathology spectrum.颅内神经肠囊肿:影像学与病理学表现谱
AJNR Am J Neuroradiol. 2006 Jun-Jul;27(6):1211-6.
4
Retroclival ecchordosis physaliphora: MR imaging and review of the literature.斜坡后脊索瘤样囊肿:磁共振成像及文献复习
AJNR Am J Neuroradiol. 2004 Nov-Dec;25(10):1851-5.
5
A multidisciplinary team approach to skull base chordomas.一种针对颅底脊索瘤的多学科团队治疗方法。
J Neurosurg. 2001 Aug;95(2):175-83. doi: 10.3171/jns.2001.95.2.0175.
6
Ecchordosis physaliphora as a cause of fatal pontine hemorrhage.
Eur Neurol. 1982;21(2):90-3. doi: 10.1159/000115460.
7
Intradural chordoma without bone involvement: nuclear magnetic resonance (NMR) appearance. Case report.无骨质受累的硬膜内脊索瘤:核磁共振成像表现。病例报告。
J Neurosurg. 1983 Sep;59(3):535-7. doi: 10.3171/jns.1983.59.3.0535.
8
Nasopharyngeal and cervical chordoma--some aspects of their development and treatment.
J Laryngol Otol. 1967 Dec;81(12):1337-55. doi: 10.1017/s0022215100068341.
9
[Chordoma of the clivus as a cause of cerebral hemorrhage: anatomoclinical discussion of an autopsied case].
Boll Soc Ital Biol Sper. 1974 Jul 30;50(12):912-8.
10
Ecchordosis physaliphora and chordoma: a comparative ultrastructural study.泡状脊索瘤与脊索瘤:一项超微结构对比研究
Clin Neuropathol. 1985 Mar-Apr;4(2):77-86.