Behavioral plus pharmacological treatment versus pharmacological treatment only for chronic migraine with medication overuse after day-hospital withdrawal.

Chronic migraine with medication overuse is a difficult problem to manage. Different withdrawal approaches have been tried, with different results. Withdrawal in a day-hospital setting is a recent modality. Results obtained from this last approach have been encouraging. Behavioral techniques combined with pharmacological therapies are effective to enforce the clinical improvement in chronic migraine patients with medication overuse. In this study, a clinical experience where day-hospital withdrawal is followed by pharmacological treatment and on the other side pharmacological treatment is combined with behavioral approach is discussed.