Stewart J T
Department of Invasive Cardiology, Royal Brompton and National Heart Hospital, London.
J Med Eng Technol. 1991 May-Jun;15(3):99-106. doi: 10.3109/03091909109016206.
Percutaneous transluminal coronary angioplasty (PTCA) is now capable of providing myocardial revascularization in a majority of patients, but significant problems with the technique remain. It is unsuitable for dealing with diffuse coronary artery disease, chronically occluded vessels may be impossible to disobliterate, and disease of the distal coronary vessel may be difficult to reach with a balloon. Approximately 5 percent of all procedures may be complicated by acute occlusion of the target vessel, usually by dissection of the arterial intima, often resulting in a need for emergency coronary artery bypass surgery (CABG). Furthermore, there is recurrence of the dilated lesion--'restenosis'--in approximately 30 percent of cases in the first 3 to 6 months after PTCA. Advances in this technique, since its introduction in the mid 1970s, have been directed at making initial success more likely, obviating the need for emergency CABG, and reducing the incidence of restenosis.
经皮腔内冠状动脉成形术（PTCA）目前能够为大多数患者实现心肌血运重建，但该技术仍存在重大问题。它不适用于处理弥漫性冠状动脉疾病，慢性闭塞血管可能无法再通，且冠状动脉远端血管疾病可能难以用球囊触及。所有手术中约5%可能因靶血管急性闭塞而复杂化，通常是由于动脉内膜撕裂，这常常导致需要进行急诊冠状动脉旁路移植术（CABG）。此外，在PTCA后的前3至6个月内，约30%的病例中扩张病变会复发——即“再狭窄”。自20世纪70年代中期引入该技术以来，其进展一直致力于提高初始成功率、避免急诊CABG的必要性以及降低再狭窄的发生率。
