Reifart N, Kupka J, Störger H, Preusler W, Schwarz F
Abteilung Kardiologie, Rotes-Kreuz-Krankenhaus, Frankfurt, Main.
Z Kardiol. 1991 May;80(5):317-21.
Acute vascular occlusion after percutaneous transluminal coronary angioplasty (PTCA) often necessitates a prompt aortocoronary bypass-operation (CABG). Alternatively, a re-PTCA can be attempted. In 1500 consecutive patients there was acute symptomatic occlusion due to PTCA 5 min to 16 h after the operation in 47 cases (3.1%). An immediate re-PTCA was attempted in all cases.
Reopening was successful in 43 of 47 cases (91%): in 15 patients (30%) within 30 min, in 36 patients (68%) within 60 min and in 42 patients (89%) within 90 min. In eight patients there was early re-occlusion 30 min to 20 h after re-PTCA, necessitating acute CABG in four patients. In 35 patients with re-PTCA the vessel remained open. Re-stenosis occurred within 1 to 10 days in 10 patients, and in additional 12 patients after 2-4 months. In most cases an additional PTCA was successful.
Six patients had an emergency CABG (three with an exchange wire as a stent in the dissected coronary artery). Three patients died (one after CABG); 14 patients experienced myocardial infarction (30%) (in three of these 14 the infarct was large).
Acute vascular occlusion after PTCA can successfully be treated by re-PTCA in four of five cases. However a rate of re-stenosis of about 60% is to be anticipated. Reperfusion with re-PTCA is fast and in these patients with transmural ischemia there are obviously less complications in comparison to emergency CABG after PTCA. 60% of the patients remain symptom free or markedly improved and without infarction or emergency CABG after 4 months.
经皮腔内冠状动脉成形术(PTCA)后急性血管闭塞常常需要及时进行主动脉冠状动脉搭桥手术(CABG)。或者,可以尝试再次进行PTCA。在1500例连续患者中,有47例(3.1%)在术后5分钟至16小时因PTCA出现急性症状性闭塞。所有病例均尝试立即进行再次PTCA。
47例中有43例(91%)再通成功:15例(30%)在30分钟内,36例(68%)在60分钟内,42例(89%)在90分钟内。8例患者在再次PTCA后30分钟至20小时出现早期再闭塞,其中4例需要进行急性CABG。35例接受再次PTCA的患者血管保持通畅。10例患者在1至10天内发生再狭窄,另外12例在2至4个月后发生。大多数情况下,再次进行PTCA成功。
6例患者进行了急诊CABG(3例在解剖的冠状动脉中使用交换导丝作为支架)。3例患者死亡(1例在CABG后);14例患者发生心肌梗死(30%)(其中14例中有3例梗死面积较大)。
PTCA后急性血管闭塞在五分之四的病例中通过再次PTCA可成功治疗。然而,预计再狭窄率约为60%。再次PTCA再灌注迅速,与PTCA后急诊CABG相比,这些透壁性缺血患者的并发症明显较少。60%的患者在4个月后无症状或症状明显改善,无梗死或急诊CABG。