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神经性厌食症患者肝功能检查异常——是因还是果。

Liver function test abnormalities in anorexia nervosa--cause or effect.

机构信息

Department of Medicine, Denver Health Medical Center, Denver, Colorado 80204, USA.

出版信息

Int J Eat Disord. 2010 May;43(4):378-81. doi: 10.1002/eat.20690.

DOI:10.1002/eat.20690
PMID:19424979
Abstract

OBJECTIVE

Two females with severe anorexia nervosa (BMI of 10) were seen with marked abnormalities in their liver function tests before the initiation of refeeding. These paradoxically resolved with progressive refeeding and weight restoration.

METHOD

Clinical observation during regimented medical stabilization and refeeding of two patients with severe anorexia nervosa with frequent monitoring of liver function tests.

RESULTS

Normalization of liver function tests ensued as caloric intake increased and weight gain progressed.

DISCUSSION

Although classically liver function test elevations occur during refeeding, as a manifestation of excessive calories and fat deposition in the liver, they may also be elevated due to severe malnutrition before refeeding has commenced and improved as refeeding occurs.

摘要

目的

两名患有严重神经性厌食症的女性(BMI 为 10)在开始重新进食前出现肝功能检查明显异常。这些异常在逐渐恢复进食和体重恢复后得到解决。

方法

对两名患有严重神经性厌食症的患者进行有规律的医疗稳定和重新进食期间的临床观察,并频繁监测肝功能检查。

结果

随着热量摄入的增加和体重的增加,肝功能检查结果恢复正常。

讨论

尽管在重新进食期间通常会出现肝功能检查升高,这是肝脏中过多卡路里和脂肪沉积的表现,但它们也可能由于重新进食前严重的营养不良而升高,并在重新进食时得到改善。

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