Sturm Marc, Kohlbacher Oliver
Center for Bioinformatics, Eberhard Karls University Tubingen, Sand 14, 72076 Tubingen, Germany.
J Proteome Res. 2009 Jul;8(7):3760-3. doi: 10.1021/pr900171m.
Visualization of complex mass spectrometric data sets is becoming increasingly important in proteomics and metabolomics. We present TOPPView, an integrated data visualization and analysis tool for mass spectrometric data sets. TOPPView allows the visualization and comparison of individual mass spectra, two-dimensional LC-MS data sets and their accompanying metadata. By supporting standardized XML-based data exchange formats, data import is possible from any type of mass spectrometer. The integrated analysis tools of the OpenMS Proteomics Pipeline (TOPP) allow efficient data analysis from within TOPPView through a convenient graphical user interface. TOPPView runs on all major operating systems and is available free of charge under an open-source license at http://www.openms.de.
在蛋白质组学和代谢组学中，复杂质谱数据集的可视化变得越来越重要。我们展示了TOPPView，这是一个用于质谱数据集的集成数据可视化和分析工具。TOPPView允许对单个质谱、二维液相色谱 - 质谱数据集及其附带的元数据进行可视化和比较。通过支持基于XML的标准化数据交换格式，可以从任何类型的质谱仪导入数据。OpenMS蛋白质组学管道（TOPP）的集成分析工具允许通过便捷的图形用户界面在TOPPView内进行高效的数据分析。TOPPView可在所有主流操作系统上运行，并根据开源许可在http://www.openms.de免费获取。
