Manoj Biswas, Sanjeev Narang, Pandurang Patil N, Jaideep Mahajani, Ravi Mahajan
Department of Urology, Institute of Urology and Kidney Research Center, Mahajan Hospital, Jalgaon, Maharashtra, India.
Urology. 2009 Aug;74(2):345-8. doi: 10.1016/j.urology.2009.02.065. Epub 2009 May 9.
To investigate the feasibility, tolerability, safety, and efficacy of using the postauricular skin graft as substitute material for anterior urethroplasty. We first reported a preliminary experience in a selected group of patients in whom the oral mucosa and genital skin were both not usable.
We retrospectively reviewed the charts of 35 patients, average age of 34 years (range, 20-64 years), who underwent urethroplasty using postauricular skin grafts for anterior urethral strictures. Stricture etiology was lichen sclerosus in 12 (35%) cases, unknown in 10 (29%), trauma in 8 (22%), and infection in 5 (14%). Of 35 strictures, 15 (43%) were classified as panurethral, 12 (34%) were in the penile urethra, and 8 (23%) in the bulbar urethra. As measured by preoperative urethrography stricture, length varies from 3-15 cm (mean stricture length, 8.9 cm). Posterior auricular skin was harvested by one team and urethral reconstruction (bulbar, penile or pan-urethral) by the other team.
Mean operative time was 190 minutes (range, 120-300 minutes). Of 35 cases, 31 (89%) were treatment successes and 4 (11%) were failures. Five patients had developed wound infections, which were treated properly as per culture sensitivity report. No patient developed diverticulum, fistula, sacculation formation, or protrusion of the graft at external meatus.
In circumcised patients with submucosal fibrosis involving the cheek oral mucosa, postauricular skin is a good substitute material for urethral reconstruction, and also in patients with lichen sclerosus stricture diseases.
探讨采用耳后皮肤移植作为前尿道成形术替代材料的可行性、耐受性、安全性和有效性。我们首次报告了一组口腔黏膜和生殖器皮肤均不可用的患者的初步经验。
我们回顾性分析了35例患者的病历,这些患者平均年龄34岁(范围20 - 64岁),因前尿道狭窄接受了耳后皮肤移植尿道成形术。狭窄病因:12例(35%)为硬化性苔藓,10例(29%)病因不明,8例(22%)为创伤,5例(14%)为感染。35处狭窄中,15处(43%)为全尿道狭窄,12处(34%)位于阴茎尿道,8处(23%)位于球部尿道。术前尿道造影测量狭窄长度为3 - 15厘米(平均狭窄长度8.9厘米)。一组医生采集耳后皮肤,另一组医生进行尿道重建(球部、阴茎或全尿道)。
平均手术时间为190分钟(范围120 - 300分钟)。35例中,31例(89%)治疗成功,4例(11%)失败。5例患者发生伤口感染,根据培养药敏报告进行了妥善治疗。无患者出现憩室、瘘管、囊袋形成或移植皮片在尿道口突出。
在包皮环切且涉及颊部口腔黏膜的黏膜下纤维化患者中,耳后皮肤是尿道重建的良好替代材料,在患有硬化性苔藓狭窄疾病的患者中也是如此。