• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Transecting the dorsal fornix results in novelty detection but not temporal ordering deficits in rats.横断大鼠背侧穹窿会导致新奇性检测障碍，但不会导致时间顺序记忆缺陷。
Behav Brain Res. 2009 Jul 19;201(1):192-7. doi: 10.1016/j.bbr.2009.02.012. Epub 2009 Feb 21.
2
A behavioral analysis of the role of CA3 and CA1 subcortical efferents during classical fear conditioning.经典恐惧条件反射过程中CA3和CA1皮质下传出神经作用的行为分析
Behav Neurosci. 2009 Jun;123(3):624-30. doi: 10.1037/a0015455.
3
A double dissociation of subcortical hippocampal efferents for encoding and consolidation/retrieval of spatial information.皮质下海马传出纤维在空间信息编码与巩固/提取方面的双重分离。
Hippocampus. 2008;18(7):699-709. doi: 10.1002/hipo.20429.
4
Dissociating the roles of dorsal and ventral CA1 for the temporal processing of spatial locations, visual objects, and odors.区分背侧和腹侧海马体CA1区在空间位置、视觉物体和气味的时间处理中的作用。
Behav Neurosci. 2008 Jun;122(3):643-50. doi: 10.1037/0735-7044.122.3.643.
5
Role of CA3 and CA1 subregions of the dorsal hippocampus on temporal processing of objects.背侧海马体CA3和CA1亚区在物体时间加工中的作用。
Neurobiol Learn Mem. 2007 Sep;88(2):225-31. doi: 10.1016/j.nlm.2007.04.013. Epub 2007 Jun 8.
6
Contribution of the dorsal subiculum to memory for temporal order and novelty detection using objects, odors, or spatial locations in the rat.大鼠背侧下托在物体、气味或空间位置的时间顺序和新颖性检测记忆中的作用。
Neurobiol Learn Mem. 2010 Mar;93(3):330-6. doi: 10.1016/j.nlm.2009.11.007. Epub 2009 Nov 26.
7
Role of dCA3 efferents via the fimbria in the acquisition of a delay nonmatch to place task.经穹窿的背侧海马3区传出纤维在位置延迟不匹配任务习得中的作用。
Hippocampus. 2007;17(6):494-502. doi: 10.1002/hipo.20288.
8
Differential roles of the dorsal hippocampal regions in the acquisition of spatial and temporal aspects of episodic-like memory.背侧海马区域在情景记忆的空间和时间方面获取中的差异作用。
Behav Brain Res. 2012 Jun 15;232(1):269-77. doi: 10.1016/j.bbr.2012.04.022. Epub 2012 Apr 21.
9
Adaptability to changes in temporal structure is fornix-dependent.对时间结构变化的适应性依赖于穹窿。
Learn Mem. 2015 Jul 15;22(8):354-9. doi: 10.1101/lm.038851.115. Print 2015 Aug.
10
Disruption of the direct perforant path input to the CA1 subregion of the dorsal hippocampus interferes with spatial working memory and novelty detection.背侧海马体CA1亚区的直接穿通通路输入中断会干扰空间工作记忆和新奇性检测。
Behav Brain Res. 2008 Jun 3;189(2):273-83. doi: 10.1016/j.bbr.2008.01.002. Epub 2008 Jan 15.

引用本文的文献

1
The differences of the precommissural and postcommissural fornix in the hippocampal location: a diffusion tensor tractography study.海马位置中连合前穹窿和连合后穹窿的差异：一项扩散张量纤维束成像研究。
Neuroradiology. 2017 Apr;59(4):397-401. doi: 10.1007/s00234-017-1817-z. Epub 2017 Mar 16.
2
Interindividual variation in fornix microstructure and macrostructure is related to visual discrimination accuracy for scenes but not faces.穹窿结构的微观和宏观个体间变异性与场景而非面孔的视觉辨别准确性有关。
J Neurosci. 2014 Sep 3;34(36):12121-6. doi: 10.1523/JNEUROSCI.0026-14.2014.

本文引用的文献

1
A behavioral analysis of the role of CA3 and CA1 subcortical efferents during classical fear conditioning.经典恐惧条件反射过程中CA3和CA1皮质下传出神经作用的行为分析
Behav Neurosci. 2009 Jun;123(3):624-30. doi: 10.1037/a0015455.
2
Dissociating the roles of dorsal and ventral CA1 for the temporal processing of spatial locations, visual objects, and odors.区分背侧和腹侧海马体CA1区在空间位置、视觉物体和气味的时间处理中的作用。
Behav Neurosci. 2008 Jun;122(3):643-50. doi: 10.1037/0735-7044.122.3.643.
3
A double dissociation of subcortical hippocampal efferents for encoding and consolidation/retrieval of spatial information.皮质下海马传出纤维在空间信息编码与巩固/提取方面的双重分离。
Hippocampus. 2008;18(7):699-709. doi: 10.1002/hipo.20429.
4
Evaluating the differential roles of the dorsal dentate gyrus, dorsal CA3, and dorsal CA1 during a temporal ordering for spatial locations task.评估在空间位置任务的时间排序过程中，齿状回背侧、CA3背侧和CA1背侧的不同作用。
Hippocampus. 2008;18(9):955-64. doi: 10.1002/hipo.20455.
5
Disruption of the direct perforant path input to the CA1 subregion of the dorsal hippocampus interferes with spatial working memory and novelty detection.背侧海马体CA1亚区的直接穿通通路输入中断会干扰空间工作记忆和新奇性检测。
Behav Brain Res. 2008 Jun 3;189(2):273-83. doi: 10.1016/j.bbr.2008.01.002. Epub 2008 Jan 15.
6
Gradual changes in hippocampal activity support remembering the order of events.海马体活动的逐渐变化有助于记住事件的顺序。
Neuron. 2007 Nov 8;56(3):530-40. doi: 10.1016/j.neuron.2007.08.017.
7
Dissociations across the dorsal-ventral axis of CA3 and CA1 for encoding and retrieval of contextual and auditory-cued fear.CA3和CA1背腹轴在情境性和听觉线索性恐惧的编码与提取过程中的分离。
Neurobiol Learn Mem. 2008 Jan;89(1):61-9. doi: 10.1016/j.nlm.2007.08.016. Epub 2007 Oct 10.
8
Dissociations of the medial and lateral perforant path projections into dorsal DG, CA3, and CA1 for spatial and nonspatial (visual object) information processing.内侧和外侧穿通通路向背侧齿状回、海马体CA3区和CA1区的投射在空间和非空间（视觉对象）信息处理方面的分离。
Behav Neurosci. 2007 Aug;121(4):742-50. doi: 10.1037/0735-7044.121.4.742.
9
The role of the direct perforant path input to the CA1 subregion of the dorsal hippocampus in memory retention and retrieval.直接穿通通路输入到背侧海马体CA1亚区在记忆保持和提取中的作用。
Hippocampus. 2007;17(10):977-87. doi: 10.1002/hipo.20329.
10
Role of CA3 and CA1 subregions of the dorsal hippocampus on temporal processing of objects.背侧海马体CA3和CA1亚区在物体时间加工中的作用。
Neurobiol Learn Mem. 2007 Sep;88(2):225-31. doi: 10.1016/j.nlm.2007.04.013. Epub 2007 Jun 8.

横断大鼠背侧穹窿会导致新奇性检测障碍，但不会导致时间顺序记忆缺陷。

Transecting the dorsal fornix results in novelty detection but not temporal ordering deficits in rats.

作者信息

Hunsaker Michael R, Kesner Raymond P

机构信息

Program in Neuroscience, University of California, Newton Court, Davis, CA 95616, USA.

出版信息

Behav Brain Res. 2009 Jul 19;201(1):192-7. doi: 10.1016/j.bbr.2009.02.012. Epub 2009 Feb 21.

DOI:10.1016/j.bbr.2009.02.012
PMID:19428633
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2680774/
Abstract

It has been shown that CA1 subserves temporal ordering processes in the hippocampus. It has also recently been shown that transecting the subcortical outputs of dorsal CA1 via the dorsal fornix results in retrieval deficits similar to those seen after lesions to CA1. The present experiment was designed to evaluate the effects of disrupting CA1 subcortical outputs for the temporal processing of visual objects and for a visual object novelty detection paradigm. The results of the present study suggest that CA1 subcortical efferents are not critically involved in temporal processing of visual objects, but are critically involved in visual object novelty detection. The data also suggest that temporal processing and novelty detection may potentially be subserved by independent mechanisms in CA1.

摘要

研究表明，CA1在海马体中参与时间排序过程。最近还发现，通过背侧穹窿切断背侧CA1的皮质下输出会导致检索缺陷，类似于CA1损伤后所见的情况。本实验旨在评估破坏CA1皮质下输出对视觉对象的时间处理和视觉对象新奇性检测范式的影响。本研究结果表明，CA1皮质下传出纤维在视觉对象的时间处理中并非关键参与，但在视觉对象新奇性检测中起关键作用。数据还表明，时间处理和新奇性检测可能由CA1中的独立机制潜在地支持。