Vladimirov B
Khirurgiia (Sofiia). 1991;44(1):8-12.
Results are reported of endoscopic treatment of 79 patients with atypical anatomical variants and anomalies of the bile ducts: common bile duct calculosis (54), stenosing papillo-odditis (8), indurative pancreatitis (2) and bile duct cancer (15). The following endoscopic manipulations have been performed: endoscopic sphincterotomy (72); hydrostatic balloon extraction of calculi (27); hydrostatic balloon dilatation of constricted segments (29); mechanical lithotripsy (15); nasolabial drainage (17) and endoprosthesis (15). Much more difficult was the extraction of calculi from the common bile in the event of atypical anatomical variants and anomalies of the distal portion of the common bile duct (chi 2 = 14.55; p less than 0.001). Treatment resulted in significant reduction of the bilirubin levels (t = 4.13; p less than 0.001), of AP (t = 4.47; p less than 0.001), GGTP (t = 4.07; p less than 0.001); AcAT (t = 5.75; p less than 0.001) and AlAT (t = 5.63; p less than 0.001). Complications occurred in 6 per cent of the patients (acute pancreatitis, cholangitis, hemorrhage). Mortality from endoscopic treatment was 1.3 per cent. Endoscopic methods for treatment are advised as alternative to operative treatment for patients in advanced age and high operative risk.
报告了对79例胆管存在非典型解剖变异和异常的患者进行内镜治疗的结果:胆总管结石病(54例)、狭窄性乳头炎(8例)、硬化性胰腺炎(2例)和胆管癌(15例)。已进行了以下内镜操作:内镜括约肌切开术(72例);结石的水压球囊取出术(27例);狭窄段的水压球囊扩张术(29例);机械碎石术(15例);鼻胆管引流术(17例)和内置假体术(15例)。在胆总管远端存在非典型解剖变异和异常的情况下,从胆总管中取出结石要困难得多(χ² = 14.55;p < 0.001)。治疗导致胆红素水平显著降低(t = 4.13;p < 0.001)、碱性磷酸酶(t = 4.47;p < 0.001)、γ-谷氨酰转肽酶(t = 4.07;p < 0.001)、乙酰转移酶(t = 5.75;p < 0.001)和谷丙转氨酶(t = 5.63;p < 0.001)。6%的患者出现了并发症(急性胰腺炎、胆管炎、出血)。内镜治疗的死亡率为1.3%。建议将内镜治疗方法作为高龄和手术风险高的患者手术治疗的替代方法。