Vladimirov B, Iordanov I
Khirurgiia (Sofiia). 1990;43(6):34-40.
Of 570 ERHP performed in patients with biliary tract and pancreas diseases, duodenal diverticuli were found in 67 (11.8 per cent). Diverticuli were more frequently diagnosed in patients beyond 60 years of age (67.2 per cent). In 83.6 per cent the diverticuli were single, mostly measuring 15-30 mm and localized in the peripapillary area (70 per cent). ERHP was successful in 85 per cent. Diverticuli were most frequently accompanied by stenosing papillo-odditis (82 per cent), cholecystitis (67 per cent), common bile duct calculosis (58 per cent), followed by pancreatitis (37 per cent) and cancer of the bile ducts (4.5 per cent). Endoscopic treatment was conducted in 46 cases: endoscopic sphincterotomy, hydrostatic balloon dilation of narrowed segments, hydrostatic balloon extraction of calculi, mechanical lithotripsy, nasolabial drainage and endoprosthesis. Significantly lower was the technical success of endoscopic sphincterotomy (78 per cent) when compared with its performance in patients without diverticuli (99 per cent). In spite of this, complex endoscopic treatment resulted in significant fall of bilirubin level (t = 6.58; p less than 0.0001), of AP (t = 8.15; p less than 0.001), of GGJP (t = 6.99; p less than 0.0001), of AcAT (t = 7.14; p less than 0.01). The incidence of complications (6.5 per cent) was not higher than the one observed in patients without diverticuli. In conclusion, endoscopic treatment of bile duct diseases is recommended to be performed also in patients with diverticuli, especially in adult patients and in those exposed to increased operative risk.
在570例接受内镜逆行胰胆管造影术(ERHP)的胆道和胰腺疾病患者中,发现十二指肠憩室67例(11.8%)。60岁以上患者中憩室的诊断更为频繁(67.2%)。83.6%的憩室为单发,大多直径为15 - 30毫米,位于乳头周围区域(70%)。ERHP成功率为85%。憩室最常伴有乳头狭窄性胆管炎(82%)、胆囊炎(67%)、胆总管结石(58%),其次是胰腺炎(37%)和胆管癌(4.5%)。46例患者接受了内镜治疗:内镜括约肌切开术、狭窄段的水囊扩张、结石的水囊取出、机械碎石、鼻胆管引流和内置假体。与无憩室患者相比,内镜括约肌切开术的技术成功率显著降低(78%对比99%)。尽管如此,复杂的内镜治疗导致胆红素水平显著下降(t = 6.58;p < 0.0001)、碱性磷酸酶(AP)下降(t = 8.15;p < 0.001)、γ - 谷氨酰转肽酶(GGJP)下降(t = 6.99;p < 0.0001)、天冬氨酸氨基转移酶(AcAT)下降(t = 7.14;p < 0.01)。并发症发生率(6.5%)并不高于无憩室患者。总之,建议对有憩室的患者,尤其是成年患者和手术风险增加的患者,也进行胆管疾病的内镜治疗。