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[慢性复发性角膜炎和干燥性角膜炎患者使用素高捷疗眼膏和含2.4%半胱氨酸眼膏的双盲法]

[Double-blind method of using solcoseryl ophthalmic gel and 2,4% cysteine in ophthalmic gel in patients with chronic recurrent keratitis and keratitis sicca].

作者信息

Krzystkowa K M, Hydzikowa M, Szpytma R

机构信息

Pracowni Patofizjologii Widzenia i Neurookulistyki przy Katedrze Okulistyki AM w Krakowie.

出版信息

Klin Oczna. 1991 Jun;93(6):162-3.

PMID:1942917
Abstract

A double blind study with Solcoseryl compounds in ophthalmic gel and with 2.4% cystein in ophthalmic gel was performed in the period 1985-1988; it was used in 18 cases: with chronic recurrent keratitis (11 patients) and sicca keratitis (7 patients). Observed was the influence of these compounds on the epithelialization of the cornea, on the improvement of corneal transparency, the diminutation of the troubles connected with dessication of the eye in sicca keratitis. In spite of the small number of cases the observations were interesting. In patients with a chronic recurrent keratitis the influence of both compounds showed to be beneficial for the condition of the cornea. In patients with keratitis sicca one could observe a better tolerance of the Solcoseryl ophthalmic gel which could be applied for a longer period in comparison with cystein in gel.

摘要

1985年至1988年期间,开展了一项针对眼用凝胶中素高捷疗化合物以及含2.4%半胱氨酸的眼用凝胶的双盲研究;该研究应用于18例患者:慢性复发性角膜炎患者(11例)和干燥性角膜炎患者(7例)。观察了这些化合物对角膜上皮化的影响、对角膜透明度改善的影响以及对干燥性角膜炎中与眼干燥相关问题的减轻作用。尽管病例数量较少,但观察结果很有意思。在慢性复发性角膜炎患者中,两种化合物的影响均显示对角膜状况有益。在干燥性角膜炎患者中,可以观察到素高捷疗眼用凝胶的耐受性更好,与凝胶中的半胱氨酸相比,其应用时间可以更长。

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