Studer O
Ophthalmic Res. 1984;16(3):179-84. doi: 10.1159/000265314.
Solcoseryl, a protein-free haemodialysate, promotes tissue regeneration and improves utilization of oxygen in the cell. In a randomized, double-blind, clinical study, Solcoseryl Eye-Gel was compared with Cysteine Eye-Gel in the treatment of foreign-body injuries of the cornea in a total of 99 eyes. In order to facilitate objective evaluation of the effects of the treatment, the area of the lesion before the start of treatment and on the following day was determined by means of slit-lamp photographs. Healing of the lesion and relative reduction of the area of the wound were observed much more frequently in the group treated with Solcoseryl Eye-Gel than in the reference group. Maculae corneae after the end of the treatment were significantly less frequent under Solcoseryl Eye-Gel than under Cysteine Eye-Gel. Teh tolerability of the test preparation was good; an itching sensation was reported in only 2 cases. Under Cysteine Eye-Gel, on the other hand, a burning sensation was reported by a number of patients and very fine deposits in the epithelium were also observed in a few cases. Thus complete closure of the epithelium over the lesion after 1 day was observed much more frequently in the group of patients treated with Solcoseryl Eye-Gel than in the reference group (63 vs. 53%).
素高捷疗，一种无蛋白的血液透析液，可促进组织再生并改善细胞内的氧利用。在一项随机、双盲临床研究中，将素高捷疗眼膏与半胱氨酸眼膏用于治疗共99只眼睛的角膜异物损伤进行比较。为便于客观评估治疗效果，通过裂隙灯照相确定治疗开始前及次日的病变面积。与参照组相比，使用素高捷疗眼膏治疗的组中，病变愈合及伤口面积相对减小的情况更为常见。治疗结束后，使用素高捷疗眼膏出现角膜斑翳的情况明显少于使用半胱氨酸眼膏。试验制剂耐受性良好；仅2例报告有瘙痒感。另一方面，使用半胱氨酸眼膏时，一些患者报告有烧灼感，少数病例还观察到上皮内有非常细小的沉积物。因此，与参照组相比，使用素高捷疗眼膏治疗的患者组中，1天后病变处上皮完全闭合的情况更为常见（63%对53%）。
