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通过荧光变化实现水中高选择性氰化物传感及其在体内成像中的应用。

A highly selective cyanide sensing in water via fluorescence change and its application to in vivo imaging.

作者信息

Chung So-Young, Nam Seong-Won, Lim Jeesun, Park Sungsu, Yoon Juyoung

机构信息

Department of Chemistry and Nano Science, Ewha Womans University, Seoul, Korea.

出版信息

Chem Commun (Camb). 2009 May 28(20):2866-8. doi: 10.1039/b901140d. Epub 2009 Mar 30.

DOI:10.1039/b901140d
PMID:19436892
Abstract

Among the various anions, only cyanide induced the revival of fluoresecence of -Cu(2+) resulting in "Off-On" type sensing of cyanide, which can be monitored at pH 7.4 in 100% aqueous system, and has been applied to a microfluidic platform, in which fluorescent sensor -Cu(2+) displayed green fluorescence upon the addition of cyanide, the in vivo imaging of cyanide using Caenorhabditis elegans.

摘要

在各种阴离子中,只有氰化物能使-Cu(2+)的荧光恢复,从而实现对氰化物的“关-开”型传感,这种传感可在pH 7.4的100%水性体系中监测,并且已应用于微流控平台,在该平台中,荧光传感器-Cu(2+)在添加氰化物时显示绿色荧光,还用于秀丽隐杆线虫对氰化物的体内成像。

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