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用于成像和传感分析物转化应用的绿色和红色荧光染料：一种双色标记。

Green and Red Fluorescent Dyes for Translational Applications in Imaging and Sensing Analytes: A Dual-Color Flag.

作者信息

Oliveira Elisabete, Bértolo Emilia, Núñez Cristina, Pilla Viviane, Santos Hugo M, Fernández-Lodeiro Javier, Fernández-Lodeiro Adrian, Djafari Jamila, Capelo José Luis, Lodeiro Carlos

机构信息

BIOSCOPE Group UCIBIO-LAQV-REQUIMTE Departamento de Química, Faculdade de Ciências e Tecnologia Universidade NOVA de Lisboa 2829-516 Lisboa Portugal.

Proteomass Scientific Society Rua dos Inventores, Madan Park 2829-516 Caparica Portugal.

出版信息

ChemistryOpen. 2017 Nov 7;7(1):9-52. doi: 10.1002/open.201700135. eCollection 2018 Jan.

DOI:10.1002/open.201700135
PMID:29318095
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5754553/
Abstract

Red and green are two of the most-preferred colors from the entire chromatic spectrum, and red and green dyes are widely used in biochemistry, immunohistochemistry, immune-staining, and nanochemistry applications. Selective dyes with green and red excitable chromophores can be used in biological environments, such as tissues and cells, and can be irradiated with visible light without cell damage. This critical review, covering a period of five years, provides an overview of the most-relevant results on the use of red and green fluorescent dyes in the fields of bio-, chemo- and nanoscience. The review focuses on fluorescent dyes containing chromophores such as fluorescein, rhodamine, cyanine, boron-dipyrromethene (BODIPY), 7-nitobenz-2-oxa-1,3-diazole-4-yl, naphthalimide, acridine orange, perylene diimides, coumarins, rosamine, Nile red, naphthalene diimide, distyrylpyridinium, benzophosphole P-oxide, benzoresorufins, and tetrapyrrolic macrocycles. Metal complexes and nanomaterials with these dyes are also discussed.

摘要

红色和绿色是整个色谱中最受欢迎的两种颜色，红色和绿色染料广泛应用于生物化学、免疫组织化学、免疫染色和纳米化学应用中。具有绿色和红色可激发发色团的选择性染料可用于生物环境，如组织和细胞，并且可以用可见光照射而不会对细胞造成损伤。这篇涵盖五年时间的综述文章，概述了在生物科学、化学科学和纳米科学领域中使用红色和绿色荧光染料的最相关研究成果。该综述聚焦于含有发色团的荧光染料，如荧光素、罗丹明、花菁、硼二吡咯亚甲基（BODIPY）、7-硝基苯并-2-恶唑-1,3-二唑-4-基、萘二甲酰亚胺、吖啶橙、苝二酰亚胺、香豆素、玫瑰胺、尼罗红、萘二酰亚胺、二苯乙烯基吡啶、苯并磷酰氧化物、苯并试卤灵，以及四吡咯大环化合物。还讨论了含有这些染料的金属配合物和纳米材料。

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