客体结合驱动空穴主体中的可逆阻转异构现象。

Guest binding drives reversible atropisomerism in cavitand hosts.

作者信息

Nguyen Thanh V, Sinclair David J, Willis Anthony C, Sherburn Michael S

机构信息

Research School of Chemistry, Australian National University, Canberra, ACT 0200, Australia.

出版信息

Chemistry. 2009 Jun 8;15(24):5892-5. doi: 10.1002/chem.200900695.

DOI:10.1002/chem.200900695

PMID:19437468

Abstract

Guest-love-ometer: The equilibrium inside-outside atropisomeric ratio of ortho-substituted phenyl cavitands shows a strong solvent dependence. The competition between the ortho-substituent and the solvent guest for the bowl cavity leads to a sensitive system for the measurement of relative guest binding affinities.

摘要