预防对比剂肾病：问题、挑战与未来方向。
Preventing contrast-induced nephropathy: problems, challenges and future directions.
作者信息
Solomon Richard
机构信息
University of Vermont College of Medicine, Burlington, VT 05405-0068, USA.
出版信息
BMC Med. 2009 May 13;7:24. doi: 10.1186/1741-7015-7-24.
Abstract
Contrast-induced nephropathy is an injury to the kidney occurring as a result of exposure to intravascular contrast media. It results in both short- and long-term adverse events including mortality. Since treatment of the injury after it has occurred is ineffective, efforts to prevent the injury are the focus of investigators and clinicians alike. In this commentary, the pathogenesis and clinical relevance of contrast-induced nephropathy are reviewed. Prophylactic strategies are discussed with a focus on the use of meta-analysis of small single-center trials.
摘要
对比剂肾病是由于血管内注射对比剂而导致的肾脏损伤。它会引发短期和长期的不良事件，包括死亡。由于损伤发生后进行治疗效果不佳，预防损伤成为研究人员和临床医生的关注焦点。在这篇评论中，我们回顾了对比剂肾病的发病机制和临床相关性。我们讨论了预防策略，重点是对小型单中心试验的荟萃分析的应用。
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