Salvioli G P, Faldella G, Schettini F, Rigillo N, Massellis G, Mollica G, Guerresi V, Bianchini E
Istituto Clinico di Pediatria Preventiva e Neonatologia, Università di Bologna.
Minerva Pediatr. 1991 Jul-Aug;43(7-8):499-503.
A multicentre study was carried out in a sample population of healthy volunteers in order to assess the usefulness of assaying serum ferritin to monitor the extent of reserves in subjects with a risk of iron deficiency. A total of 317 subjects were included in the study. Ninety-nine were children with a mean age of 19 months, 121 were adolescents with a mean age of 18 years and 7 months, and 97 were women with a mean age of 28 years and 9 months. Levels of serum ferritin below the normal minimum levels for each age bracket, an indication of the exhaustion of the body's reserves, were found in 29% of children, 32.2% of adolescents and 27.8% of women. This study therefore confirm the frequent onset, even in our modern society, of iron-deficient states at particular times of life and that these are easily overlooked. The measurements of serum ferritin levels, in addition to being a confirmatory test in cases of suspected sideropenic anemia, has the peculiar characteristic of being the only test able to identify risk subjects before they become symptomatic. This enables rapid treatment to be commenced or better, efficient prevention.
为了评估检测血清铁蛋白对于监测缺铁风险人群储备铁水平的有用性，在健康志愿者样本群体中开展了一项多中心研究。共有317名受试者纳入该研究。其中99名是儿童，平均年龄为19个月；121名是青少年，平均年龄为18岁7个月；97名是女性，平均年龄为28岁9个月。在各年龄组中，血清铁蛋白水平低于正常最低水平，这表明身体储备铁已耗尽，在29%的儿童、32.2%的青少年和27.8%的女性中发现了这种情况。因此，本研究证实，即使在现代社会，缺铁状态在特定生命阶段也经常出现，而且这些情况很容易被忽视。血清铁蛋白水平的检测，除了作为疑似缺铁性贫血病例的确诊试验外，还具有一个独特的特点，即它是唯一能够在风险人群出现症状之前识别他们的检测方法。这使得能够迅速开始治疗，或者更好地进行有效预防。
