Mezzani Alessandro, Agostoni Piergiuseppe, Cohen-Solal Alain, Corrà Ugo, Jegier Anna, Kouidi Evangelia, Mazic Sanja, Meurin Philippe, Piepoli Massimo, Simon Attila, Laethem Christophe Van, Vanhees Luc
S Maugeri Foundation, Veruno Scientific Institute, Cardiology Division, Veruno (NO), Italy.
Eur J Cardiovasc Prev Rehabil. 2009 Jun;16(3):249-67. doi: 10.1097/HJR.0b013e32832914c8.
Cardiopulmonary exercise testing (CPET) is a methodology that has profoundly affected the approach to patients' functional evaluation, linking performance and physiological parameters to the underlying metabolic substratum and providing highly reproducible exercise capacity descriptors. This study provides professionals with an up-to-date review of the rationale sustaining the use of CPET for functional evaluation of cardiac patients in both the clinical and research settings, describing parameters obtainable either from ramp incremental or step constant-power CPET and illustrating the wealth of information obtainable through an experienced use of this powerful tool. The choice of parameters to be measured will depend on the specific goals of functional evaluation in the individual patient, namely, exercise tolerance assessment, training prescription, treatment efficacy evaluation, and/or investigation of exercise-induced adaptations of the oxygen transport/utilization system. The full potentialities of CPET in the clinical and research setting still remain largely underused and strong efforts are recommended to promote a more widespread use of CPET in the functional evaluation of cardiac patients.
心肺运动试验(CPET)是一种对患者功能评估方法产生了深远影响的技术,它将运动表现和生理参数与潜在的代谢基础联系起来,并提供高度可重复的运动能力描述指标。本研究为专业人员提供了一份最新综述,阐述了在临床和研究环境中支持使用CPET对心脏病患者进行功能评估的理论依据,描述了从斜坡递增或阶梯恒功率CPET中可获得的参数,并说明了通过熟练运用这一强大工具可获取的丰富信息。要测量的参数选择将取决于个体患者功能评估的具体目标,即运动耐力评估、训练处方、治疗效果评估和/或对运动诱导的氧运输/利用系统适应性的研究。CPET在临床和研究环境中的全部潜力仍在很大程度上未得到充分利用,建议做出大力努力,以促进CPET在心脏病患者功能评估中的更广泛应用。