Juchems M S, Ernst A S, Sheafor D H, Carrascosa P, Virmany S, Brambs H-J, Aschoff A J
Klinik für Diagnostische und Interventionelle Radiologie, Universitätskliniken Ulm.
Rofo. 2009 Jun;181(6):573-8. doi: 10.1055/s-0028-1109143. Epub 2009 May 13.
The purpose of this multicenter study was to compare a dissection display and an endoluminal display for CT colonography (CTC) by means of detection rates and evaluation time in a screening collective.
4 blinded readers evaluated CTC datasets from 42 patients with 55 endoscopically confirmed polyps. The datasets were read in a randomized order using two different 3D visualization methods (endoluminal view vs. dissection display; EBW 2.0.1, Philips Medical Systems, Best/NL). Patients underwent cathartic cleansing as well as stool and fluid tagging. All readers except one were experienced in performing CTC. The per-lesion/per-patient sensitivity, per-patient specificity, and evaluation time were calculated.
The overall per-lesion sensitivity using the dissection display (and endoluminal view) was 60% (53 %) for reader 1, 58% (60%) for reader 2, 67% (71%) for reader 3 and 55% (58%) for reader 4. The per-patient sensitivity using the dissection display (and endoluminal view) was 85% (85%) for reader 1, 80% (85%) for reader 2, 95% (90%) for reader 3 and 80% (80%) for reader 4. The per-patient specificity was 68% with dissection view (77% endoluminal view) for reader 1, 82% (82%) for reader 2, 59% (59%) for reader 3 and 82% (73%) for reader 4. The experienced readers were significantly faster using the perspective-filet view.
Using a dissection display of CTC datasets does not result in superior detection rates for polyps if datasets are stool and fluid-tagged. 3 out of 4 readers evaluated the datasets significantly faster with the dissection display.
这项多中心研究的目的是通过筛查人群中的检出率和评估时间，比较CT结肠成像（CTC）的解剖显示和腔内显示。
4名盲法阅片者评估了42例患者的CTC数据集，这些患者有55个经内镜证实的息肉。使用两种不同的3D可视化方法（腔内视图与解剖显示；EBW 2.0.1，飞利浦医疗系统公司，荷兰贝斯特）以随机顺序读取数据集。患者接受了导泻清洁以及粪便和液体标记。除一名阅片者外，所有阅片者都有进行CTC的经验。计算了每个病变/每个患者的敏感性、每个患者的特异性以及评估时间。
对于阅片者1，使用解剖显示（和腔内视图）时每个病变的总体敏感性为60%（53%），阅片者2为58%（60%），阅片者3为67%（71%），阅片者4为55%（58%）。使用解剖显示（和腔内视图）时每个患者的敏感性，阅片者1为85%（85%），阅片者2为80%（85%），阅片者3为95%（90%），阅片者4为80%（80%）。阅片者1使用解剖视图时每个患者的特异性为68%（腔内视图为77%），阅片者2为82%（82%），阅片者3为59%（59%），阅片者4为82%（73%）。经验丰富的阅片者使用透视文件视图时速度明显更快。
如果数据集进行了粪便和液体标记，使用CTC数据集的解剖显示对息肉的检出率并不会更高。4名阅片者中有3名使用解剖显示评估数据集的速度明显更快。
