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从良性阵发性位置性眩晕的外科治疗中吸取的经验教训:大学健康网络后半规管阻塞手术的经验(1988 - 2006年)

Lessons learned from the surgical management of benign paroxysmal positional vertigo: the University Health Network experience with posterior semicircular canal occlusion surgery (1988-2006).

作者信息

Kisilevsky Vitaly, Bailie Neil A, Dutt Sunil N, Rutka John A

机构信息

Department of Otolaryngology, University Health Network, Toronto, Ontario.

出版信息

J Otolaryngol Head Neck Surg. 2009 Apr;38(2):212-21.

Abstract

OBJECTIVE

To assess the long-term efficacy and safety of posterior semicircular canal (PSCC) occlusion for intractable and incapacitating benign paroxysmal positional vertigo (BPPV) and identify lessons that may be learned from our experience.

STUDY DESIGN

Retrospective review.

SETTING

Tertiary referral centre.

METHODS

Clinical records and results of audiometric and vestibular testing were reviewed on a series of patients who underwent occlusion of the PSCC for intractable BPPV between 1988 and 2006.

OUTCOME MEASURES

Postoperative neurotologic examination, audiometry, and vestibular testing were assessed.

RESULTS

Thirty-two PSCC occlusion procedures were performed (24 females, 8 males; mean age 46 years). The average follow-up was 63 months. All patients had complete resolution of their PSCC positional vertigo, which has been maintained long term. Thirteen patients (40%) have experienced other forms of dizziness postoperatively (contralateral BPPV in four, continued Meniere disease attacks in three, ipsilateral lateral or superior canal BPPV in two, otolithic symptoms in two, continued oscillopsia in one, and subsequent cerebellar degeneration in one). Postoperative audiometry demonstrated an average reduction in pure-tone threshold of 6.1, 6.3, and 6.9 dB at 0.5 to 3, 4, and 8 kHz, respectively. Five patients had a mild to moderate reduction in caloric activity in the operated ear postoperatively. Two patients with Meniere disease had a significant postoperative caloric reduction. No patient had postoperative facial weakness.

CONCLUSIONS

PSCC occlusion is a safe and highly effective treatment for intractable BPPV. However, other forms of vertigo may persist or arise subsequently in approximately 40% of cases. Patients with Meniere disease may be susceptible to increased caloric reduction postoperatively.

摘要

目的

评估后半规管(PSCC)阻塞术治疗难治性和致残性良性阵发性位置性眩晕(BPPV)的长期疗效和安全性,并总结从我们的经验中可吸取的教训。

研究设计

回顾性研究。

研究地点

三级转诊中心。

方法

对1988年至2006年间因难治性BPPV接受PSCC阻塞术的一系列患者的临床记录以及听力和前庭测试结果进行回顾。

观察指标

评估术后神经耳科学检查、听力测定和前庭测试结果。

结果

共进行了32例PSCC阻塞手术(女性24例,男性8例;平均年龄46岁)。平均随访时间为63个月。所有患者的PSCC位置性眩晕均完全缓解,并长期保持。13例患者(40%)术后出现了其他形式的头晕(4例为对侧BPPV,3例为梅尼埃病持续发作,2例为同侧外侧或上半规管BPPV,2例为耳石症症状,1例为持续视振荡,1例为随后出现小脑变性)。术后听力测定显示,在0.5至3、4和8kHz时,纯音阈值平均分别降低了6.1、6.3和6.9dB。5例患者术后患侧耳的冷热试验反应有轻度至中度降低。2例梅尼埃病患者术后冷热试验反应有显著降低。无患者出现术后面部无力。

结论

PSCC阻塞术是治疗难治性BPPV的一种安全且高效的方法。然而,约40%的病例可能会持续存在或随后出现其他形式的眩晕。梅尼埃病患者术后可能更容易出现冷热试验反应降低。

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