[Therapy of recurrent herpes simplex].

The topical and systemic possibilities of treatment of herpes simplex recidivans are discussed in a brief report. The antigen therapy with Lupidon is mentioned in detail. A selection of important clinical reports on Lupidon is commented. These reports demonstrate a good to very good therapeutic effect of Lupidon in relapsing herpes simplex with more than 1500 controlled patients. A statistically confirmed result of the long-term antigen therapy with Lupidon was particularly demonstrated in controlled double blank tests. Up to now there were not observed any severe side effects with this great number of patients.