[Immunotherapy of recurrent Herpes simplex diseases].

Different methods of immunotherapy in patients with recurrent herpes simplex diseases are reported. The clinical improvement after immunostimulation with heterologous or homologous antigens is demonstrated. The results of different authors are summarized and compared with our own results. In ten patients the lymphocyte stimulation was studied with the lymphocyte transformation test (LTT) as a parameter for cell-mediated immunity. The LTT was performed before immunotherapy and four months later. No difference was found in the lymphocyte stimulation by phytohaemagglutinine or by an antigen, containing heat-inactivated herpes simplex virus.