走向神经性厌食症的神经回路：来自功能神经影像学研究的证据。
Towards a neurocircuitry in anorexia nervosa: evidence from functional neuroimaging studies.
作者信息
van Kuyck Kris, Gérard Nathalie, Van Laere Koen, Casteels Cindy, Pieters Guido, Gabriëls Loes, Nuttin Bart
机构信息
Laboratory for Experimental Functional Neurosurgery, Department of Neurosciences, K.U.Leuven Provisorium I, Minderbroedersstraat 17, 3000 Leuven, Belgium.
出版信息
J Psychiatr Res. 2009 Sep;43(14):1133-45. doi: 10.1016/j.jpsychires.2009.04.005. Epub 2009 May 13.
Functional neuroimaging is widely used to unravel changes in brain functioning in psychiatric disorders. In the current study, we review single-photon emission tomography (SPECT), positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) studies in anorexia nervosa (AN), a difficult-to-treat eating disorder with the highest mortality rate among psychiatric disorders. We discuss the role of the parietal cortex, anterior and subgenual cingulate cortex, frontal cortex and temporal lobe in light of the cardinal symptoms of AN. The insights of the current review may ultimately lead to the development of new treatments.
功能神经成像被广泛用于揭示精神疾病中大脑功能的变化。在当前的研究中，我们回顾了针对神经性厌食症（AN）的单光子发射断层扫描（SPECT）、正电子发射断层扫描（PET）和功能磁共振成像（fMRI）研究，神经性厌食症是一种难以治疗的饮食失调症，在精神疾病中死亡率最高。我们根据神经性厌食症的主要症状，讨论了顶叶皮质、前扣带回和膝下扣带回皮质、额叶皮质和颞叶的作用。当前综述的见解可能最终会促成新治疗方法的开发。
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