Koslowsky Donna J
Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI 48824, USA.
Trends Parasitol. 2009 Jun;25(6):252-5. doi: 10.1016/j.pt.2009.03.008. Epub 2009 May 13.
Trypanosomes undergo extreme physiological changes to adapt to different environments as they cycle between hosts. Adaptation to the different environments has evolved an energy metabolism involving a mitochondrion with an unusual genome. Recently, Aphasizhev and colleagues have identified two new protein complexes, a mitochondrial polyadenylation complex and a guide RNA stabilization complex, that provide novel insights into the coordinated expression of the mitochondrial genome.
锥虫在宿主间循环时会经历极端的生理变化以适应不同环境。对不同环境的适应进化出了一种能量代谢，涉及具有异常基因组的线粒体。最近，阿法西热夫及其同事鉴定出了两种新的蛋白质复合物，一种线粒体多聚腺苷酸化复合物和一种引导RNA稳定复合物，它们为线粒体基因组的协调表达提供了新的见解。
