Wise Lauren A, Palmer Julie R, Rothman Emily F, Rosenberg Lynn
Slone Epidemiology Center, 1010 Commonwealth Ave, Boston, MA 02215, USA.
Am J Public Health. 2009 Oct;99 Suppl 2(Suppl 2):S460-6. doi: 10.2105/AJPH.2008.149005. Epub 2009 May 14.
We examined the association between childhood abuse and early menarche in a sample of US Black women.
We conducted multivariable log-binomial regression on data from 35 330 participants in the Black Women's Health Study to estimate risk ratios and 95% confidence intervals for the relation of childhood physical and sexual abuse with early age at menarche (i.e., < 12 years).
In adjusted analyses, sexual abuse was positively associated with early menarche, and the risk of early menarche increased with increasing frequency of sexual abuse incidents. We observed a weak but statistically significant association between physical abuse and early menarche. Associations between sexual abuse and early menarche were stronger when we used a more stringent cutpoint for early menarche (i.e., < 11 years).
Our data suggest an increased risk of early menarche among Black women who experienced childhood sexual abuse. Evidence for an association between childhood physical abuse and early menarche was equivocal.
我们在美国黑人女性样本中研究了童年期受虐经历与初潮过早之间的关联。
我们对黑人女性健康研究中35330名参与者的数据进行了多变量对数二项回归分析,以估计童年期身体虐待和性虐待与初潮过早(即<12岁)之间关系的风险比及95%置信区间。
在调整分析中,性虐待与初潮过早呈正相关,初潮过早的风险随着性虐待事件发生频率的增加而升高。我们观察到身体虐待与初潮过早之间存在微弱但具有统计学意义的关联。当我们采用更严格的初潮过早切点(即<11岁)时,性虐待与初潮过早之间的关联更强。
我们的数据表明,童年期遭受性虐待的黑人女性初潮过早的风险增加。童年期身体虐待与初潮过早之间存在关联的证据并不明确。