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儿童新型及新发现呼吸道病毒综述。

Review of new and newly discovered respiratory tract viruses in children.

作者信息

Brodzinski Holly, Ruddy Richard M

机构信息

Division of Emergency Medicine, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

出版信息

Pediatr Emerg Care. 2009 May;25(5):352-60; quiz 361-3. doi: 10.1097/PEC.0b013e3181a3497e.

DOI:10.1097/PEC.0b013e3181a3497e
PMID:19444037
Abstract

Respiratory tract viral infection continues to be among the most common reasons for emergency department visits and hospitalization of children, particularly infants younger than 1 year, in the United States. Throughout the years, clinicians have considered respiratory syncytial virus followed by influenza as the most common pathogens responsible. Over the past decade, new viruses have been discovered through both more specific testing and the finding of new agents causing infection. This includes human metapneumovirus, which leads to similar but often epidemiologically more severe clinical symptoms than respiratory syncytial virus. Other agents responsible for lower respiratory tract infection include Coronavirus (severe acute respiratory syndrome), Bocavirus, and others. This review serves to focus on some of the recent literature on these agents and the clinical impact they have on pediatric lung infection.

摘要

在美国,呼吸道病毒感染仍然是儿童前往急诊科就诊和住院的最常见原因之一,尤其是1岁以下的婴儿。多年来,临床医生一直认为呼吸道合胞病毒其次是流感是最常见的致病病原体。在过去十年中,通过更具针对性的检测以及发现新的感染病原体,发现了一些新病毒。这包括人偏肺病毒,它导致的临床症状与呼吸道合胞病毒相似,但在流行病学上往往更严重。其他导致下呼吸道感染的病原体包括冠状病毒(严重急性呼吸综合征)、博卡病毒等。这篇综述旨在关注有关这些病原体的一些最新文献以及它们对小儿肺部感染的临床影响。

相似文献

1
Review of new and newly discovered respiratory tract viruses in children.儿童新型及新发现呼吸道病毒综述。
Pediatr Emerg Care. 2009 May;25(5):352-60; quiz 361-3. doi: 10.1097/PEC.0b013e3181a3497e.
2
[SARS, avian influenza, and human metapneumovirus infection].[严重急性呼吸综合征、禽流感和人偏肺病毒感染]
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[Etiological structure of influenza and other ARVI in St. Petersburg during epidemic seasons 2012-2016.].[2012 - 2016年流行季节圣彼得堡流感及其他急性呼吸道病毒感染的病因结构。]
Vopr Virusol. 2018;63(5):233-239. doi: 10.18821/0507-4088-2018-63-5-233-239.
4
Two-year prospective study of single infections and co-infections by respiratory syncytial virus and viruses identified recently in infants with acute respiratory disease.对呼吸道合胞病毒及近期在患有急性呼吸道疾病的婴儿中发现的病毒的单一感染和合并感染进行的两年前瞻性研究。
J Med Virol. 2008 Apr;80(4):716-23. doi: 10.1002/jmv.21108.
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Newer respiratory virus infections: human metapneumovirus, avian influenza virus, and human coronaviruses.新型呼吸道病毒感染:人偏肺病毒、禽流感病毒和人冠状病毒。
Curr Opin Infect Dis. 2005 Apr;18(2):141-6. doi: 10.1097/01.qco.0000160903.56566.84.
6
Role of human metapneumovirus, human coronavirus NL63 and human bocavirus in infants and young children with acute wheezing.人偏肺病毒、人冠状病毒NL63和人博卡病毒在急性喘息婴幼儿中的作用。
J Med Virol. 2008 May;80(5):906-12. doi: 10.1002/jmv.21135.
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[Emerging respiratory infections caused by pneumotropic viruses].[嗜肺病毒引起的新发呼吸道感染]
Dtsch Med Wochenschr. 2005 Jun 3;130(22):1385-91. doi: 10.1055/s-2005-868739.
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Unpredictable patterns of viral respiratory disease in children.
Pediatrics. 2004 Jun;113(6):1814-6. doi: 10.1542/peds.113.6.1814.
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The clinical presentation and outcomes of children infected with newly identified respiratory tract viruses.新发现的呼吸道病毒感染儿童的临床表现及预后
Infect Dis Clin North Am. 2005 Sep;19(3):569-84. doi: 10.1016/j.idc.2005.05.009.
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Human bocavirus infection in children with respiratory tract disease.呼吸道疾病患儿的人博卡病毒感染
Pediatr Infect Dis J. 2008 Nov;27(11):969-73. doi: 10.1097/INF.0b013e31817acfaa.

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PLoS Pathog. 2022 Jun 2;18(6):e1010578. doi: 10.1371/journal.ppat.1010578. eCollection 2022 Jun.
2
The Large Nonstructural Protein (NS1) of Human Bocavirus 1 Directly Interacts with Ku70, Which Plays an Important Role in Virus Replication in Human Airway Epithelia.人博卡病毒 1 的大非结构蛋白(NS1)与人呼吸道上皮细胞中的 Ku70 直接相互作用,Ku70 在病毒复制中发挥重要作用。
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发夹转移非依赖细小病毒 DNA 复制产生感染性病毒。
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A Prospective Study of Etiological Agents Among Febrile Patients in Sierra Leone.塞拉利昂发热患者病因学因素的前瞻性研究。
Infect Dis Ther. 2021 Sep;10(3):1645-1664. doi: 10.1007/s40121-021-00474-y. Epub 2021 Jun 26.
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Systematic review and meta-analysis of the prevalence of common respiratory viruses in children < 2 years with bronchiolitis in the pre-COVID-19 pandemic era.在 COVID-19 大流行之前,对儿童<2 岁毛细支气管炎常见呼吸道病毒流行率的系统评价和荟萃分析。
PLoS One. 2020 Nov 12;15(11):e0242302. doi: 10.1371/journal.pone.0242302. eCollection 2020.
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Expert Rev Clin Immunol. 2019 Aug;15(8):869-878. doi: 10.1080/1744666X.2019.1642748. Epub 2019 Jul 25.
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DNA Damage Signaling Is Required for Replication of Human Bocavirus 1 DNA in Dividing HEK293 Cells.DNA损伤信号传导是人类博卡病毒1 DNA在分裂的HEK293细胞中复制所必需的。
J Virol. 2016 Dec 16;91(1). doi: 10.1128/JVI.01831-16. Print 2017 Jan 1.
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Analysis of cis and trans Requirements for DNA Replication at the Right-End Hairpin of the Human Bocavirus 1 Genome.人博卡病毒1型基因组右端发夹结构处DNA复制的顺式和反式需求分析
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Hospital admission due to respiratory viral infections in moderate preterm, late preterm and term infants during their first year of life.中度早产、晚期早产和足月儿在出生后第一年因呼吸道病毒感染而住院的情况。
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PCR testing for paediatric acute respiratory tract infections.儿童急性呼吸道感染的聚合酶链反应检测
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