儿童急性呼吸道感染的聚合酶链反应检测
PCR testing for paediatric acute respiratory tract infections.
作者信息
Wishaupt Jérôme O, Versteegh Florens G A, Hartwig Nico G
机构信息
Department of Paediatrics, Reinier de Graaf Hospital, Delft, The Netherlands.
Department of Paediatrics, Groene Hart Ziekenhuis, Gouda, The Netherlands and Department of Paediatrics, Ghent University Hospital, Gent, Belgium.
出版信息
Paediatr Respir Rev. 2015 Jan;16(1):43-8. doi: 10.1016/j.prrv.2014.07.002. Epub 2014 Aug 5.
Abstract
Acute respiratory tract infection (ARI) is a frequently occurring disease in children. It is a clinical diagnosis for which no internationally accepted diagnostic test is available. The majority of ARI is viral in origin, though diagnostic tests for viruses were rarely performed in the past. In the past 2 decades, new molecular techniques have been introduced in many hospitals. They are capable of generating a high yield of viral and bacterial diagnoses, but their impact upon clinical practices is still questionable. In this paper, we discuss the difficulties of diagnosing ARI in children, the indications for conventional and new diagnostics and their implications.
摘要
急性呼吸道感染（ARI）是儿童常见疾病。这是一种临床诊断，目前尚无国际公认的诊断检测方法。尽管过去很少进行病毒诊断检测，但大多数ARI源于病毒感染。在过去20年里，许多医院引入了新的分子技术。这些技术能够大幅提高病毒和细菌诊断率，但其对临床实践的影响仍值得怀疑。在本文中，我们讨论了儿童ARI诊断的困难、传统和新诊断方法的适应症及其影响。
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