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表现为腰椎神经根病的滑膜软骨瘤病

Synovial chondromatosis presenting with lumbar radiculopathy.

作者信息

Kim Sang Woo, Choi Joon Hyuk

机构信息

Department of Neurosurgery, College of Medicine, Yeungnam University, Daegu, Korea.

出版信息

Spine (Phila Pa 1976). 2009 May 15;34(11):E414-7. doi: 10.1097/BRS.0b013e3181a2dc5c.

DOI:10.1097/BRS.0b013e3181a2dc5c
PMID:19444055
Abstract

STUDY DESIGN

A case report of lumbar synovial chondromatosis with radiculopathy.

OBJECTIVE

To report a case of synovial chondromatosis of a lumbar facet joint that extended into the spinal canal and compromised the lumbar nerve root and raised spinal surgeons' awareness of the possibility of this unusual clinical problem.

SUMMARY OF BACKGROUND DATA

Synovial chondromatosis is an uncommon disorder characterized by the formation of multiple cartilaginous nodules in the synovium of a facet joint. It most commonly affects large joints. Synovial chondromatosis in the spine is rare and there is no previous report of associated lumbar radiculopathy.

METHODS

A 24-year-old woman presented with low back pain and right sciatica lasting 5 months. There was no objective weakness. Computed tomography scans showed multiple calcified nodules anterior and medial to the right apophyseal joint of L5-S1 and extending into the spinal canal. Magnetic resonance imaging showed a lobulated, heterogeneous enhancing extradural mass arising from the anteromedial aspect of the right L5-S1 facet joint. The lesion was removed in multiple pieces with curette after exposure of the corresponding intervertebral space through a conventional interlaminar approach. The histologic examination showed nodules of hyaline cartilage beneath the synovial cell lining.

RESULTS

The patient was completely free of low back pain and right sciatica 5 days after the surgery. All neurologic tests were normal from that point onwards.

CONCLUSION

Synovial chondromatosis may compromise lumbar nerve roots when it extends into the spinal canal from the facet joint. Although synovial chondromatosis of the lumbar spine is rare, it should be included in the differential diagnosis of radiculopathy.

摘要

研究设计

腰椎滑膜软骨瘤病伴神经根病的病例报告。

目的

报告一例腰椎小关节滑膜软骨瘤病,该病变延伸至椎管并压迫腰神经根,以提高脊柱外科医生对这一罕见临床问题的认识。

背景资料总结

滑膜软骨瘤病是一种罕见疾病,其特征是在小关节滑膜中形成多个软骨结节。它最常累及大关节。脊柱滑膜软骨瘤病很罕见,此前尚无伴发腰神经根病的报道。

方法

一名24岁女性,下腰痛和右下肢坐骨神经痛持续5个月。无客观肌无力表现。计算机断层扫描显示L5 - S1右侧关节突关节前内侧有多个钙化结节,并延伸至椎管内。磁共振成像显示一个分叶状、不均匀强化的硬膜外肿块,起源于右侧L5 - S1小关节的前内侧。通过传统的椎板间入路暴露相应椎间隙后,用刮匙分块切除病变。组织学检查显示滑膜细胞内衬下方有透明软骨结节。

结果

术后5天,患者下腰痛和右下肢坐骨神经痛完全消失。此后所有神经学检查均正常。

结论

当滑膜软骨瘤病从小关节延伸至椎管时,可能会压迫腰神经根。虽然腰椎滑膜软骨瘤病罕见,但在神经根病的鉴别诊断中应考虑到该病。

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