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表现为硬膜外肿块的滑膜软骨瘤病。

Synovial chondromatosis presenting as an epidural mass.

作者信息

Mehra Ratnesh Nandan, Grigorov Marat, Pieper Daniel

机构信息

Department of Neurosurgery, St. John Providence Health System, Southfield, Michigan, USA.

Department of Neurosurgery, Michigan Head and Spine Institute, Southfield, Michigan, USA.

出版信息

Surg Neurol Int. 2015 Aug 31;6(Suppl 14):S388-90. doi: 10.4103/2152-7806.163961. eCollection 2015.

DOI:10.4103/2152-7806.163961
PMID:26425399
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4566305/
Abstract

BACKGROUND

Synovial chondromatosis is an uncommon disorder characterized by the formation of multiple cartilaginous nodules in the synovium of the facet joint. It most commonly affects large joints such as hip or shoulder. Commonly seen features are bony erosion and calcifications. Synovial chondromatosis is rare in the spine and there are few previous reports of extension into the spinal canal.

CASE DESCRIPTION

A 58-year-old man presented with a 2 year history of progressive numbness in the right upper extremity without objective weakness. A several month course of conservative management, including physical therapy, failed to alleviate symptoms. Magnetic resonance imaging of the cervical spine demonstrated the erosion of the right facet C5-C6 joint with listhesis and foraminal enlargement secondary to a lesion. Treatment was offered to the patient in the form of surgical resection. The lesion was removed in piecemeal fashion using curettes and Cavitron ultrasonic surgical aspirator. Histological examination demonstrated atypical well-differentiated cartilaginous proliferation.

CONCLUSION

This patient had an uncomplicated postoperative course and experienced complete resolution of right upper extremity sensory symptoms. Synovial chondromatosis may compromise cervical spinal cord and nerve roots if it extends into the spinal canal. Although it remains rare, it should be included in the differential diagnosis for upper extremity radiculopathy and myelopathy. Surgical resection is a viable treatment option for symptomatic patients with this pathology. In some cases, adequate resection may necessitate stabilization with instrumentation.

摘要

背景

滑膜软骨瘤病是一种罕见的疾病,其特征是在小关节滑膜中形成多个软骨结节。它最常累及大关节,如髋部或肩部。常见特征包括骨质侵蚀和钙化。滑膜软骨瘤病在脊柱中罕见,以前很少有延伸至椎管的报道。

病例描述

一名58岁男性,有2年右上肢进行性麻木病史,无客观肌无力。包括物理治疗在内的几个月保守治疗过程未能缓解症状。颈椎磁共振成像显示C5-C6右侧小关节侵蚀,伴有椎体滑脱和继发于病变的椎间孔扩大。以手术切除的形式为患者提供了治疗。使用刮匙和Cavitron超声手术吸引器以碎块形式切除病变。组织学检查显示非典型的高分化软骨增生。

结论

该患者术后过程顺利,并完全缓解了右上肢感觉症状。滑膜软骨瘤病如果延伸至椎管,可能会累及颈脊髓和神经根。尽管它仍然罕见,但在鉴别诊断上肢神经根病和脊髓病时应予以考虑。手术切除是有症状的此类患者可行的治疗选择。在某些情况下,充分切除可能需要器械固定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53db/4566305/3a23a1b2b9ae/SNI-6-388-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53db/4566305/ee81a2aba56a/SNI-6-388-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53db/4566305/0aaa93395736/SNI-6-388-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53db/4566305/3a23a1b2b9ae/SNI-6-388-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53db/4566305/ee81a2aba56a/SNI-6-388-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53db/4566305/0aaa93395736/SNI-6-388-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53db/4566305/3a23a1b2b9ae/SNI-6-388-g003.jpg

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本文引用的文献

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2
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3
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Spine (Phila Pa 1976). 2000 Mar 1;25(5):635-40. doi: 10.1097/00007632-200003010-00018.
4
青少年双侧肘滑膜软骨瘤病:病例报告及文献复习。
BMC Musculoskelet Disord. 2020 Jun 13;21(1):377. doi: 10.1186/s12891-020-03322-1.
Vertebral synovial osteochondromatosis with compressive myelopathy.
Spine (Phila Pa 1976). 1999 May 1;24(9):921-3. doi: 10.1097/00007632-199905010-00017.