Linder Patrick, Owttrim George W
Department of Microbiology and Molecular Medicine, CMU, 1 Rue Michel Servet, CH-1211 Geneve 4, Switzerland.
Trends Plant Sci. 2009 Jun;14(6):344-52. doi: 10.1016/j.tplants.2009.03.007. Epub 2009 May 14.
RNA helicases are ATPases that are capable of rearranging RNA and ribonucleoprotein (RNP) structure, and they can potentially function in any aspect of RNA metabolism. The RNA helicase gene family of plant genomes is larger and more diverse than genome families observed in other systems and provides an ideal model for investigation of the physiological importance of RNA secondary structure rearrangement in plant development. Numerous plant RNA helicases are associated with a variety of physiological functions, but this review will focus on the thirteen RNA helicases associated with the metabolism of aberrant and silencing RNAs. The results emphasize the crucial role RNA helicase activity has in the regulation of mRNA quality control and gene expression in plant development.
RNA解旋酶是一类ATP酶，能够重新排列RNA和核糖核蛋白（RNP）的结构，并且它们可能在RNA代谢的任何方面发挥作用。植物基因组中的RNA解旋酶基因家族比在其他系统中观察到的基因组家族更大且更多样化，为研究RNA二级结构重排在植物发育中的生理重要性提供了理想模型。许多植物RNA解旋酶与多种生理功能相关，但本综述将聚焦于与异常RNA和沉默RNA代谢相关的13种RNA解旋酶。结果强调了RNA解旋酶活性在植物发育中mRNA质量控制和基因表达调控方面的关键作用。
