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髂静脉完全闭塞的经皮再通术。

Percutaneous recanalization of total occlusions of the iliac vein.

作者信息

Raju Seshadri, Neglén Peter

机构信息

University of Mississippi Medical Center, Jackson, Miss, USA.

出版信息

J Vasc Surg. 2009 Aug;50(2):360-8. doi: 10.1016/j.jvs.2009.01.061. Epub 2009 May 15.

Abstract

BACKGROUND

Venovenous bypass has been the standard in relieving chronic total occlusions of iliac veins. The technical feasibility of percutaneous recanalization was previously reported. Routine applicability of this technique in a wide spectrum of lesions and patients, stent patency, and clinical outcome forms the basis of this presentation.

METHODS

During a 9-year period, 167 limbs in 159 unselected patients in a consecutive series with post-thrombotic chronic total occlusions of the iliac and adjacent vein segments underwent percutaneous attempts at recanalization. Patients were not selected based on venographic appearance or extent of the lesion, or excluded because of a preemptive choice of open venovenous bypass surgery.

RESULTS

Percutaneous recanalization was successful in 139 of 167 limbs (83%), including patients with bilateral occlusions and 14 patients with inferior vena cava filters incorporated in the treated occlusion. Median age was 53 years (range, 18-84 years). Thrombophilia was identified in 44 patients. Venous dermatitis/ulcer was found in 46% of the treated limbs. Recanalization involved three or more totally occluded vein segments in 42% of the limbs. The cumulative secondary stent patency rate at 4 years was 66%. The cumulative marked relief of pain and swelling at 3 years was 79% and 66%, respectively. Cumulative healing of venous ulcer at 33 months was 56%. Quality of life metrics improved significantly.

CONCLUSIONS

Most femoroiliocaval chronic total occlusions lesions can be successfully recanalized percutaneously with very little morbidity, minimal downtime, sustained long-term stent patency, and substantial clinical improvement. The procedure has wide applicability in a broad spectrum of symptomatic patients, including those with extensive lesions, and can be considered for routine use.

摘要

背景

静脉-静脉转流术一直是缓解髂静脉慢性完全闭塞的标准方法。先前已报道了经皮再通术的技术可行性。本技术在广泛的病变和患者中的常规适用性、支架通畅性及临床结果构成了本报告的基础。

方法

在9年期间,对159例未经选择的连续系列患者的167条肢体进行了血栓形成后髂静脉及相邻静脉段慢性完全闭塞的经皮再通尝试。患者并非根据静脉造影表现或病变范围进行选择,也未因优先选择开放性静脉-静脉转流手术而被排除。

结果

167条肢体中有139条(83%)经皮再通成功,包括双侧闭塞患者及14例在治疗闭塞中置入下腔静脉滤器的患者。中位年龄为53岁(范围18 - 84岁)。44例患者存在易栓症。46%的治疗肢体出现静脉性皮炎/溃疡。42%的肢体再通涉及三个或更多完全闭塞的静脉段。4年时支架累计二次通畅率为66%。3年时疼痛和肿胀的累计显著缓解率分别为79%和66%。33个月时静脉溃疡的累计愈合率为56%。生活质量指标显著改善。

结论

大多数股髂腔静脉慢性完全闭塞病变可通过经皮成功再通,发病率极低,停机时间最短,支架长期通畅,临床有显著改善。该手术在广泛的有症状患者中具有广泛适用性,包括病变广泛的患者,可考虑常规使用。

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