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Acute risk of drug-related death among newly released prisoners in England and Wales.英格兰和威尔士新获释囚犯中与药物相关死亡的急性风险。
Addiction. 2008 Feb;103(2):251-5. doi: 10.1111/j.1360-0443.2007.02081.x.
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Suicidal behaviour and associated risk factors among opioid-dependent individuals: a case-control study.阿片类药物依赖者的自杀行为及相关危险因素:一项病例对照研究。
Addiction. 2007 Dec;102(12):1933-41. doi: 10.1111/j.1360-0443.2007.01971.x. Epub 2007 Sep 3.
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Non-fatal heroin overdose, treatment exposure and client characteristics: findings from the Australian treatment outcome study (ATOS).非致命性海洛因过量、治疗接触及客户特征:澳大利亚治疗结果研究(ATOS)的发现
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Anxiety disorders associated with suicidal ideation and suicide attempts in the National Comorbidity Survey.《国家共病调查》中与自杀意念和自杀未遂相关的焦虑症
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Suicidal behaviors and drug abuse: impulsivity and its assessment.自杀行为与药物滥用:冲动性及其评估
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Impulsivity and smoking relapse.冲动性与吸烟复发。
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Lack of association between the serotonin transporter promoter gene polymorphism and impulsivity or aggressive behavior among suicide attempters and healthy volunteers.自杀未遂者和健康志愿者中血清素转运体启动子基因多态性与冲动性或攻击性行为之间缺乏关联。
Psychiatry Res. 2004 Apr 30;126(2):99-106. doi: 10.1016/j.psychres.2003.10.007.
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Attempted suicide among entrants to three treatment modalities for heroin dependence in the Australian Treatment Outcome Study (ATOS): prevalence and risk factors.澳大利亚治疗结果研究(ATOS)中接受三种海洛因依赖治疗方式的患者的自杀未遂情况:患病率及风险因素。
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非致命性阿片类药物过量是否被错误归类为自杀未遂?比较相关的关联因素。

Are non-fatal opioid overdoses misclassified suicide attempts? Comparing the associated correlates.

机构信息

National Drug and Alcohol Research Centre, University of New South Wales, Sydney NSW 2052, Australia.

出版信息

Addict Behav. 2009 Sep;34(9):723-9. doi: 10.1016/j.addbeh.2009.04.011. Epub 2009 May 3.

DOI:10.1016/j.addbeh.2009.04.011
PMID:19447563
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2730501/
Abstract

This paper aimed to determine whether non-fatal opioid overdose and suicide attempts are distinct behaviours by examining the histories of 1500 opioid-dependent individuals. This paper utilised data collected as part of a large retrospective case-control study. Unintentional non-fatal opioid overdoses were more common than suicide attempts (58% vs. 32%). Overall, the correlates associated with a history of attempted suicide only and non-fatal opioid overdose only were different. Drug-related risk behaviours (including high impulsivity, injection of opioids, sedative dependence) were associated with non-fatal opioid overdose; and a history of mental disorders (depression, anxiety disorder, and screening positive for borderline personality disorder (BPD+) were associated with suicide attempts. Additionally, those who reported a history of both behaviours had a more severe clinical profile including excessive drug use, psychological disorders and childhood trauma. The study concluded that non-fatal opioid overdose and attempted suicide are distinct clinically significant problems that require different approaches for prevention. Additionally, if both behaviours are reported a thorough assessment of underlying comorbid problems should be initiated by treatment services.

摘要

本研究旨在通过对 1500 名阿片类药物依赖者的既往史进行研究,确定非致命性阿片类药物过量和自杀未遂是否为不同的行为。本研究利用了作为一项大型回顾性病例对照研究的一部分所收集的数据。非致命性阿片类药物过量比自杀未遂更为常见(58%比 32%)。总体而言,与仅自杀未遂史和非致命性阿片类药物过量史相关的因素不同。与非致命性阿片类药物过量相关的药物相关风险行为(包括高冲动性、阿片类药物注射、镇静剂依赖);与自杀未遂相关的是精神障碍史(抑郁症、焦虑障碍和边缘型人格障碍筛查阳性(BPD+)。此外,报告有这两种行为史的患者具有更严重的临床特征,包括过度用药、心理障碍和童年创伤。该研究得出结论,非致命性阿片类药物过量和自杀未遂是不同的具有临床意义的问题,需要采取不同的预防方法。此外,如果报告了这两种行为,治疗服务机构应启动对潜在共病问题的全面评估。