Shirakawa N, Mukai K, Fujisawa H, Furuichi S
Fujisawa Neurosurgical Hospital.
No Shinkei Geka. 1991 Sep;19(9):897-902.
A case of intraventricular cyst associated with normal pressure hydrocephalic condition (NPHC) is reported. A 72 year-old female, with 2-year-history of slowly progressing dementia and gait disturbance, was admitted to our hospital on September 19, 1989. On admission, she had mild dementia, unsteadiness of gait, and at times urinary incontinence. Cerebrospinal fluid (CSF) pressure was found to be 90mmH2O by lumbar tap. Plain computed tomographic (CT) scan and T1-weighted magnetic resonance image (MRI) showed asymmetrical enlargement of the trigon and posterior horn of the right lateral ventricle. CT cisternography showed a cyst in the trigon and in the posterior horn of the right lateral ventricle. T1-weighted MRI with Gd-DTPA demonstrated no enhancement of the cyst wall, and there was superior and posteromedial displacement of the choroid plexus at the trigon of the right lateral ventricle. The patient was diagnosed as having an intraventricular cyst in the right trigon with NPHC. Ventriculo-peritoneal shunt and partial removal of the cyst were performed. Histological examination of the cyst wall revealed collagenous strands and no epithelial cells. Developmental intracranial cysts, especially arachnoid or ependymal cysts, occasionally lack an epithelial layer, so their histological diagnosis is difficult. This case was considered to be an arachnoid cyst because there was adhesion between the cyst and the choroid plexus in the right trigon, and superior, posteromedial displacement of the choroid plexus, which indicated extension of the cyst from the extracerebral to the intracerebral region. NPHC was considered to be due to disturbance of CSF circulation caused by gradual expansion of the cyst.
报告了一例与正常压力脑积水(NPHC)相关的脑室内囊肿病例。一名72岁女性,有2年缓慢进展的痴呆和步态障碍病史,于1989年9月19日入住我院。入院时,她有轻度痴呆、步态不稳,有时还有尿失禁。通过腰椎穿刺发现脑脊液(CSF)压力为90mmH2O。普通计算机断层扫描(CT)和T1加权磁共振成像(MRI)显示右侧脑室三角区和后角不对称扩大。CT脑池造影显示右侧脑室三角区和后角有一个囊肿。Gd-DTPA增强的T1加权MRI显示囊肿壁无强化,右侧脑室三角区脉络丛向上和后内侧移位。该患者被诊断为右侧三角区脑室内囊肿合并NPHC。进行了脑室-腹腔分流术和囊肿部分切除术。囊肿壁的组织学检查显示有胶原束,无上皮细胞。发育性颅内囊肿,尤其是蛛网膜囊肿或室管膜囊肿,偶尔缺乏上皮层,因此其组织学诊断困难。该病例被认为是蛛网膜囊肿,因为右侧三角区囊肿与脉络丛之间有粘连,且脉络丛向上、后内侧移位,这表明囊肿从脑外延伸至脑内区域。NPHC被认为是由于囊肿逐渐扩大导致脑脊液循环障碍所致。