Hashimoto T, Tayama M, Miyazaki M, Kuroda Y
Department of Pediatrics, Tokushima University School of Medicine, Japan.
Neuropediatrics. 1991 Aug;22(3):139-46. doi: 10.1055/s-2008-1071432.
The morphological development of the brainstem was studied by means of MR imaging. The subjects were 74 cases ranging in age from 4 months to 16 years, and 6 adult cases. The brainstem development was rapid until 4-6 years of age and thereafter it slowed down. That is the brainstem showed exponential growth (w', t', v and u). The relationship between brainstem growth and the cranium size was divided into 4 types as follows: 1) linear increase with development (s/T-O), 2) plateau (w/T-I and v/RTP-LTP), 3) down and up (u/RTM-LTM and z/RTM-LTM) and 4) exponential (t/T-P). In the values of v, z (the size of the brainstem in axial view) and t/T-P (the ratio of the midbrain and the cranium size in sagittal view), there were significant sex differences for cases of 10-16 years old. These values in male subjects were greater than those in female subjects (v, p less than 0.05, z, p less than 0.01, and t/T-P, p less than 0.05). That is the brainstem in male subjects was greater than that in female subjects.
采用磁共振成像方法研究脑干的形态发育。研究对象为74例年龄在4个月至16岁之间的儿童及6例成人。脑干发育在4至6岁前迅速，之后减缓。即脑干呈现指数增长（w'、t'、v和u）。脑干生长与颅骨大小之间的关系分为以下4种类型：1）随发育呈线性增加（s/T - O），2）平台期（w/T - I和v/RTP - LTP），3）先下降后上升（u/RTM - LTM和z/RTM - LTM），4）指数型（t/T - P）。在v、z（轴位视图中脑干大小）和t/T - P（矢状位视图中中脑与颅骨大小之比）的值方面，10至16岁的病例存在显著性别差异。男性受试者的这些值大于女性受试者（v，p < 0.05，z，p < 0.01，t/T - P，p < 0.05）。也就是说男性受试者的脑干大于女性受试者的脑干。
