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[里约热内卢州农村人口中提示眼弓形虫病的病变发生率]

[Frequency of lesions suggestive of ocular toxoplasmosis among a rural population in the State of Rio de Janeiro].

作者信息

Aleixo Ana Luisa Quintella do Couto, Benchimol Eliezer Israel, Neves Elisabeth de Souza, Silva Cassius Schnell Palhano, Coura Léa Camillo, Amendoeira Maria Regina Reis

机构信息

Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, RJ.

出版信息

Rev Soc Bras Med Trop. 2009 Mar-Apr;42(2):165-9. doi: 10.1590/s0037-86822009000200014.

Abstract

To determine the prevalence of ocular toxoplasmosis among the general population of the district of Santa Rita de Cassia, Barra Mansa, State of Rio de Janeiro, a cross-sectional study on 1,071 individuals was performed. These subjects underwent serological tests (anti-Toxoplasma IgG and IgM) and physical and ophthalmological examinations. The diagnosis of presumed ocular toxoplasmosis was based on clinical and serological criteria and the appearance of the retinochoroidal lesion. The lesions were classified into three morphological types: 1. Limits marked with a halo of hyperpigmentation and an area of central chorioretinal atrophy; 2. Hypopigmented halo and hyperpigmented central area; and 3. Hyperpigmented or hypopigmented. The prevalence of healed lesions compatible with ocular toxoplasmosis was 3.8% among the general population and 5.8% among individuals who were seropositive for Toxoplasma gondii (65.9% of the individuals evaluated). Type-1 lesions (41.5%), female sex (68.3%), peripheral lesions (58.5%) and lesions smaller than three disc diameters predominated.

摘要

为确定里约热内卢州巴拉曼萨市圣丽塔·德卡西亚区普通人群中眼弓形虫病的患病率,对1071名个体进行了一项横断面研究。这些受试者接受了血清学检测(抗弓形虫IgG和IgM)以及体格和眼科检查。疑似眼弓形虫病的诊断基于临床和血清学标准以及视网膜脉络膜病变的外观。病变分为三种形态类型:1. 边界有色素沉着过度晕圈和中央脉络膜视网膜萎缩区;2. 色素减退晕圈和色素沉着过度中央区;3. 色素沉着过度或色素减退。在普通人群中,与眼弓形虫病相符的愈合病变患病率为3.8%,在弓形虫血清学阳性个体(占评估个体的65.9%)中为5.8%。1型病变(41.5%)、女性(68.3%)、周边病变(58.5%)以及小于三个视盘直径的病变占主导。

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