Magulová L, Foltánová T
Oddelenie klinickej formakológie Fakultnej nemocnice Nitra, Slovenská republika.
Vnitr Lek. 2009 Apr;55(4):403-7.
Drug-drug interactions in diabetic patients could be serious, even life threatening. Possible manifestation of hypo/hyperglycemia as a consequence of drug-drug interactions are often wrong interpreted as a nonadherence to the diabetic diet or polymorbidity of the patient. Drug-drug interactions are not taken into account. The risk of drug-drug interactions is exponentially increasing with the number of taken drugs. In the group of diabetic patients is good to prevent the combinations of drugs, which can lead to drug-drug interactions and use alternative therapy with lower potential of drug-drug interactions. In this paper we present the possibilities of clinical pharmacist from the Department of clinical pharmacology to prevent and solve the drug-drug interactions in diabetic patients.
糖尿病患者中的药物相互作用可能很严重，甚至危及生命。药物相互作用导致的低血糖/高血糖的可能表现常常被错误地解释为患者不遵守糖尿病饮食或患有多种疾病，而未考虑药物相互作用。药物相互作用的风险会随着所服用药物数量的增加而呈指数级上升。在糖尿病患者群体中，最好避免使用可能导致药物相互作用的药物组合，并使用药物相互作用可能性较低的替代疗法。在本文中，我们展示了临床药理学部门的临床药师预防和解决糖尿病患者药物相互作用问题的可能性。
