Bugarin Alejandro, Connell Brian T
Department of Chemistry, Texas A&M University, P.O. Box 30012, College Station, Texas 77842-3012, USA.
J Org Chem. 2009 Jun 19;74(12):4638-41. doi: 10.1021/jo900603w.
By using a catalytic amount of 4-dimethylaminopyridine (DMAP) as a nucleophile in the presence of an equal amount of tetramethylethylenediamine (TMEDA) and MgI(2), Morita-Baylis-Hillman adducts can be obtained in good to excellent yields from various aromatic and aliphatic aldehydes and cyclic enones/enoates at room temperature after convenient reaction times.
通过在等量的四甲基乙二胺（TMEDA）和碘化镁（MgI₂）存在下，使用催化量的4-二甲氨基吡啶（DMAP）作为亲核试剂，在室温下经过适当的反应时间后，可从各种芳香族和脂肪族醛以及环状烯酮/烯酸酯中以良好至优异的产率获得森田-贝利斯-希尔曼加合物。
